0001558370-18-008385 Sample Contracts

AMENDMENT NO. 1 TO EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • November 2nd, 2018 • TESARO, Inc. • Pharmaceutical preparations

This Amendment No. 1 (this “Amendment”) to the Exclusive License Agreement, dated July 27, 2017 (the “Agreement”), between TESARO, Inc. (“TESARO”) and Millennium Pharmaceuticals, Inc., a wholly-owned subsidiary of Takeda Pharmaceutical Company Ltd. (“Licensee”), is entered into as of July 16, 2018 (“Amendment Effective Date”). TESARO and Licensee are sometimes referred to herein individually as a “Party” and together as the “Parties”. Capitalized terms used but not otherwise defined in this Amendment shall have the same meaning as set forth in the Agreement.

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