0001558370-21-001141 Sample Contracts

NINTH AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • February 17th, 2021 • Blueprint Medicines Corp • Pharmaceutical preparations • New York

This Ninth Amendment (this “Ninth Amendment”), effective January 8, 2021 (“Ninth Amendment Effective Date”), is by and between F. Hoffmann-La Roche Ltd, with an office and place of business at Grenzacherstrasse 124, 4070 Basel, Switzerland and Hoffmann-La Roche Inc., with an office and place of business at 150 Clove Road, Suite 8, Little Falls, New Jersey 07424 U.S.A. (together referred to as “Roche”), and Blueprint Medicines Corporation, with a principal place of business at 45 Sidney Street, Cambridge, Massachusetts 02139 U.S.A. (“BPM”). Capitalized terms used and not otherwise defined in this Ninth Amendment shall have the meanings set forth in the Agreement (as defined below).

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