0001558370-23-012633 Sample Contracts

AMENDMENT NO. 1 TO THIRD AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 1st, 2023 • uniQure N.V. • Pharmaceutical preparations

This AMENDMENT NO. 1 TO THIRD AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT (this “Amendment”), is dated as of May 12, 2023 and is entered into by and among (a) (i) UNIQURE BIOPHARMA B.V., a private limited liability company incorporated and existing under the laws of the Netherlands, having its corporate seat at Amsterdam, the Netherlands and registered at the trade register of the Chamber of Commerce for Amsterdam under number 34275365 (“uniQure Bio”), (ii) UNIQURE, INC., a Delaware corporation (“US Borrower” and together with uniQure Bio hereinafter collectively referred to as “Borrower”), (iii) UNIQURE IP B.V., a private limited liability company incorporated and existing under the laws of the Netherlands, having its corporate seat at Amsterdam, the Netherlands and registered at the trade register of the Chamber of Commerce for Amsterdam under number 34275369 (“uniQure IP”), and (iv) UNIQURE N.V. (formerly uniQure B.V.), a public limited company incorporated and existing under t

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ROYALTY PURCHASE AGREEMENT1 dated as of May 12, 2023 between UNIQURE BIOPHARMA BV and HEMB SPV, L.P.
Royalty Purchase Agreement • August 1st, 2023 • uniQure N.V. • Pharmaceutical preparations • New York

This ROYALTY PURCHASE AGREEMENT (this “Agreement”) dated as of May 12, 2023 (the “Execution Date”) is between uniQure biopharma BV (“Seller”), a corporation organized under the laws of the Netherlands, and HemB SPV, L.P., a Delaware limited partnership (“Purchaser” and collectively with Seller, the “Parties” and each, a “Party”).

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