AMENDMENT NO. 4 TO COLLABORATION AND LICENSE AGREEMENTCollaboration and License Agreement • May 2nd, 2024 • BICYCLE THERAPEUTICS PLC • Pharmaceutical preparations
This Amendment No. 4 to Collaboration and License Agreement (“Fourth Amendment”) is made and entered into effective as of January 17, 2024 (“Fourth Amendment Effective Date”) by and between BicycleTx Limited, a company incorporated in England and Wales with a place of business at Blocks A & B, Portway Building Granta Park, Great Abington, Cambridge, United Kingdom, CB21 6GS (“BicycleTx”), and Ionis Pharmaceuticals, Inc., a Delaware corporation with a principal place of business at 2855 Gazelle Court, Carlsbad, California 92010, USA (“Ionis”).
