0001559053-18-000025 Sample Contracts

Form of Option Award Agreement between Prothena Corporation plc and Registrant’s Named Executive Officers (used beginning June 21, 2018) PROTHENA CORPORATION PLC
Option Award Agreement • August 7th, 2018 • Prothena Corp PLC • Pharmaceutical preparations

Prothena Corporation plc, an Irish public limited company (the “Company”), hereby grants an Option to acquire its Shares to the individual named below. The terms and conditions of the Option are set forth in this cover sheet, in the attached Option Award Agreement and in the Prothena Corporation plc 2018 Long Term Incentive Plan (the “Plan”). All capitalized terms used but not defined in this cover sheet and the attached Option Award Agreement will have the meanings ascribed to such terms in the Plan.

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Form of Option Award Agreement between Prothena Corporation plc and Registrant’s Non-Employee Directors (used beginning May 16, 2018) PROTHENA CORPORATION PLC
Option Award Agreement • August 7th, 2018 • Prothena Corp PLC • Pharmaceutical preparations

Prothena Corporation plc, an Irish public limited company (the “Company”), hereby grants an Option to acquire its Shares to the individual named below. The terms and conditions of the Option are set forth in this cover sheet, in the attached Option Award Agreement and in the Prothena Corporation plc 2018 Long Term Incentive Plan (the “Plan”). All capitalized terms used but not defined in this cover sheet and the attached Option Award Agreement will have the meanings ascribed to such terms in the Plan.

SEPARATION AGREEMENT
Separation Agreement • August 7th, 2018 • Prothena Corp PLC • Pharmaceutical preparations • California

This Separation Agreement (this “Agreement”) by and between Tara Nickerson (“Executive”) and Prothena Biosciences Inc, a Delaware corporation (the “Company”) is made effective as of the date that the Company and Executive sign this Agreement (the “Effective Date”), with reference to the following facts:

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