0001564590-13-000333 Sample Contracts

AMENDMENT AGREEMENT
Amendment Agreement • August 13th, 2013 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances • Colorado

This AMENDMENT AGREEMENT (this “Amendment”), by and between ARCA biopharma, Inc., a Delaware corporation (the “Company”), and Patrick Wheeler (“Executive”) is effective as of June 13, 2013 (the “Effective Date”).

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ARISTA PLACE
Lease Extension Agreement • August 13th, 2013 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances

Arista Place, LLC (Landlord) agrees to a continuation of the Term of your lease for an additional three (3) month period. The financial terms presently applied to the ARCA (Tenant) lease obligations will remain the same during this additional three (3) month term.

Contract
Clinical Trial Collaboration Agreement • August 13th, 2013 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances

When countersigned by Medtronic, this letter shall serve as a permanent waiver of Medtronic’s rights under Section 8.2 (f), and ARCA’s rights under Section 8.3 (e) of the above-referenced Agreement.

AMENDMENT AGREEMENT
Employment Agreement • August 13th, 2013 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances • Colorado

This AMENDMENT AGREEMENT (this “Amendment”), by and between ARCA biopharma, Inc., a Delaware corporation (the “Company”), and Christopher D. Ozeroff (“Executive”) is effective as of June 13, 2013 (the “Effective Date”).

AMENDMENT AGREEMENT
Employment Agreement • August 13th, 2013 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances • Colorado

This AMENDMENT AGREEMENT (this “Amendment”), by and between ARCA biopharma, Inc., a Delaware corporation (the “Company”), and Michael R. Bristow (“Executive”) is effective as of June 13, 2013 (the “Effective Date”).

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