SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENTLoan and Security Agreement • January 7th, 2016 • Mast Therapeutics, Inc. • Pharmaceutical preparations • California
Contract Type FiledJanuary 7th, 2016 Company Industry JurisdictionTHIS SECOND AMENDMENT (this “Amendment”) to the Loan and Security Agreement, dated as of August 11, 2015, as previously amended pursuant to that certain First Amendment thereto dated as of September 28, 2015 (as so amended, the “Loan Agreement”), is made by and among MAST THERAPEUTICS, INC., a Delaware corporation (“Borrower”), HERCULES TECHNOLOGY GROWTH CAPITAL, INC., a Maryland corporation, as administrative agent (“Agent”), and the lender party hereto (“Lender”), and shall be effective as of December 31, 2015.