0001564590-16-013652 Sample Contracts

LICENSE AGREEMENT
License Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • California

THIS LICENSE AGREEMENT is made and entered into as of the 12th day of August 1998, by and among Mountain View Pharmaceuticals, Inc., Duke University, and Bio-Technology General Corporation.

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SUBLEASE
Office Lease Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Illinois

This Office Lease Agreement is made and entered into as of the Effective Date by and between Opus North Corporation, an Illinois corporation, as Landlord, and Solo Cup Operating Corporation, a Delaware corporation, as Tenant.

AMENDMENT NO. 1 TO SUPPLY AGREEMENT
Supply Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations

This AMENDMENT NO. 1 TO SUPPLY AGREEMENT (this “Amendment”) is made and entered into as of February 4, 2016 by and between Nuvo Research Inc., a company incorporated under the laws of the province of Ontario, Canada (“NUVO”), having offices at 7560 Airport Road, Unit 10, Mississauga, Ontario, L4T 4H4, and Horizon Pharma Ireland Limited, a Irish limited company (“HORIZON PHARMA”), and amends that certain Supply Agreement, dated as of October 17, 2014 (the “Supply Agreement”), by and between NUVO and HORIZON PHARMA. Capitalized terms used herein and not otherwise defined herein shall have the meanings assigned to such terms in the Supply Agreement.

EXECUTIVE EMPLOYMENT AGREEMENT BY AND BETWEEN HORIZON PHARMA SERVICES LIMITED AND DAVID G. KELLY
Employment Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations

This Executive Employment Agreement (hereinafter referred to as the “Agreement”), is entered into by and between Horizon Pharma Services Limited (hereinafter referred to as the “Company”) and David G. Kelly (hereinafter referred as to the “Executive”). The terms of this Agreement shall be effective commencing January 1, 2016 (the “Effective Date”).

SUPPLY AGREEMENT Dated: August 3, 2015 between CREALTA Pharmaceuticals LLC and NOF CORPORATION
Supply Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Delaware

This SUPPLY AGREEMENT (“Agreement”) is made and entered into on the 3rd day of August, 2015 by and between CREALTA Pharmaceuticals LLC., a Delaware limited liability company with offices at 150 S. Saunders Rd., Suite 130, Lake Forest, IL 60045, U.S.A. (“CREALTA”), and NOF CORPORATION, a corporation duly organized under the laws of Japan, located at 20-3, Ebisu 4-chome, Shibuya-ku, Tokyo, 150-6019, Japan (“NOF”),

COMMERCIAL SUPPLY AGREEMENT
Commercial Supply Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • New Jersey

This Commercial Supply Agreement (this “Agreement”) is entered into as of October 16, 2008, (the “Effective Date”) by and between Enzon Pharmaceuticals, Inc., a Delaware corporation with an address of 685 Route 202-206, Bridgewater, New Jersey 08807 (“Enzon”), and Savient Pharmaceuticals, Inc., a Delaware corporation, having its principal place of business at One Tower Center, 14th Floor, East Brunswick, New Jersey 08816 (“Savient”). Enzon and Savient may be referred to individually as a “Party” or collectively as “Parties.”

COMMERCIAL SUPPLY AGREEMENT
Commercial Supply Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • New York
FOR EXECUTION ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and 240.24b-2.
License and Settlement Agreement • February 29th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Delaware

This LICENSE AND SETTLEMENT AGREEMENT (this “Agreement”), dated October 1, 2015 (the “Execution Date”), is hereby entered into by and among Horizon Pharma Switzerland GmbH (formerly known as Horizon Pharma AG), a Swiss company with its principal place of business at Kagenstrasse 17, CH-4153 Reinach, Switzerland (“Horizon Pharma Switzerland”), Jagotec AG, a Swiss company with its principal place of business at Eptingerstrasse 61, CH-4132 Muttenz, Switzerland (“Jagotec”) (Horizon Pharma Switzerland and Jagotec, individually referred to as a “Licensor” and collectively referred to as “Licensors”), and Actavis Laboratories FL, Inc. (formerly known as Watson Laboratories, Inc. – Florida), a Florida Corporation with a principal place of business at 4955 Orange Drive, Davie, Florida 33314 (“Actavis”) (each individually a “Party”, collectively, “Parties”).

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