0001564590-16-014596 Sample Contracts

Amendment No. 2 to the Research Collaboration and License Agreement
Research Collaboration and License Agreement • March 11th, 2016 • Five Prime Therapeutics Inc • Pharmaceutical preparations • New York

This Amendment No. 2 to the Research Collaboration and License Agreement (this “Amendment”), effective as of July 27, 2015 (the “Amendment Effective Date”), is made by and between UCB Pharma S.A., a Belgium corporation (“UCB”), and Five Prime Therapeutics, Inc., a Delaware corporation (“FivePrime”).

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Contract
License and Collaboration Agreement • March 11th, 2016 • Five Prime Therapeutics Inc • Pharmaceutical preparations • New York

*** INDICATES MATERIAL THAT WAS OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT WAS REQUESTED. ALL SUCH OMITTED MATERIAL WAS FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24b-2 PROMULGATED UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED.

Amendment No. 1 to the Research Collaboration and License Agreement
Research Collaboration and License Agreement • March 11th, 2016 • Five Prime Therapeutics Inc • Pharmaceutical preparations

This Amendment No. 1 to the Research Collaboration and License Agreement (this “Amendment”), effective January 21, 2016 (the “Amendment Effective Date”), is made and entered into by and between Five Prime Therapeutics, Inc., a Delaware corporation (“FivePrime”), and Bristol-Myers Squibb Company, a Delaware corporation (“BMS”).

Respiratory Diseases Research Collaboration and License Agreement
Respiratory Diseases Research Collaboration and License Agreement • March 11th, 2016 • Five Prime Therapeutics Inc • Pharmaceutical preparations • Delaware

This Amendment No. 3 to the Respiratory Diseases Research Collaboration and License Agreement, effective as of January 26, 2016 (this “Amendment No. 3”), is made by and between Glaxo Group Limited, a company existing under the laws of England and Wales, having its registered office at Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex, UB6 ONN, England (“GSK”), and Five Prime Therapeutics, Inc., a Delaware corporation having a place of business at Two Corporate Drive, South San Francisco, CA 94080, USA (“FivePrime”).

Executive Transition and Severance Benefits Agreement
Executive Transition and Severance Benefits Agreement • March 11th, 2016 • Five Prime Therapeutics Inc • Pharmaceutical preparations • California

Certain capitalized terms used in this Termination Date Release are defined in the Executive Transition and Severance Benefits Agreement (the “Agreement”) which I have executed and of which this Termination Date Release is a part.

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