0001564590-16-027498 Sample Contracts

FIRST AMENDMENT TO CO-DEVELOPMENT AND COLLABORATION AGREEMENT
Confidential Materials • November 4th, 2016 • Aveo Pharmaceuticals Inc • Pharmaceutical preparations

This First Amendment (“First Amendment”) is made effective as of October 14, 2016 (“Amendment Effective Date”) and shall serve to modify that certain Co-Development and Collaboration Agreement dated April 9, 2014 (“Agreement”) by and between AVEO Pharmaceuticals, Inc. (“AVEO”) and Biodesix, Inc. (“Biodesix”). AVEO and Biodesix are sometimes referred to individually as a “Party” and collectively as the “Parties”.

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