EXECUTIVE EMPLOYMENT AGREEMENT BY AND BETWEEN HORIZON PHARMA, INC., HORIZON PHARMA USA, INC. AND DAVID A. HAPPELExecutive Employment Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Illinois
This Executive Employment Agreement (hereinafter referred to as the “Agreement”), is entered into by and between Horizon Pharma, Inc., a Delaware corporation, and its wholly owned subsidiary, Horizon Pharma USA, Inc., a Delaware corporation, each having a principal place of business at 150 S. Saunders Road, Lake Forest, IL 60045 (hereinafter referred to together as the “Company”) and David A. Happel (hereinafter referred as to the “Executive”). The terms of this Agreement shall be effective commencing October 25, 2016 (the “Effective Date”).
API SUPPLY AGREEMENTApi Supply Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • New York
This API Supply Agreement (“Agreement”) is made as of the 3rd day of November, 2010 (“Effective Date”), by and between Raptor Therapeutics, Inc., a Delaware Corporation, with a place of business at 9 Commercial Boulevard, Suite 200, Novato, California 94949, U.S.A. (“RAPTOR”), and Cambrex Profarmaco Milano, Via Cucchiari 17, 20155 Milan, Italy (“CAMBREX”). RAPTOR and CAMBREX may be referred to individually as a “Party” or collectively as the “Parties.”
Manufacturing Services Agreement November 15, 2010Manufacturing Services Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Ohio
THIS AGREEMENT WITNESSES THAT in consideration of the rights conferred and the obligations assumed herein, and for other good and valuable consideration (the receipt and sufficiency of which are acknowledged by each party), and intending to be legally bound the parties agree as follows:
CONFIDENTIAL SETTLEMENT AGREEMENT AND MUTUAL RELEASESettlement Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • Delaware
This Confidential Settlement Agreement and Mutual Release (this “Agreement”) is entered into as of September 26, 2016 by and between (a) EXPRESS SCRIPTS, INC. (“EXPRESS SCRIPTS”) and (b) HORIZON PHARMA USA, INC., (“HORIZON”). Collectively, EXPRESS SCRIPTS and HORIZON shall be referred to as the “Parties” or singularly, a “Party.”
FIFTH AMENDMENT TO COMMERCIAL SUPPLY AGREEMENTCommercial Supply Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations
THIS FIFTH AMENDMENT TO THE AGREEMENT (“Fifth Amendment”) is entered into effective as of this 31st day of August 2016 (“Fifth Amendment Effective Date”) by and between Horizon Pharma Ireland Limited (“HPIL”), an Irish company, and Bio-Technology General (Israel) Ltd., an Israeli company (“BTG” and together collectively with HPIL, “Parties”, and each individually a “Party”).
SECOND AMENDMENT [Drafted as AMENDED AND RESTATED] LICENSE AGREEMENT BETWEEN RAPTOR THERAPEUTICS, INC. AND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA FOR CASE NO. SD2006-092License Agreement • November 7th, 2016 • Horizon Pharma PLC • Pharmaceutical preparations • California
