0001564590-16-028617 Sample Contracts

Re: Amendment to Stock Option Grant Notice and Stock Option Agreement
Stock Option Agreement • November 9th, 2016 • Puma Biotechnology, Inc. • Pharmaceutical preparations

This letter of amendment (“Letter of Amendment”) is intended to notify you that the Compensation Committee of the Board of Directors of the Company has approved an amendment to the Stock Option Agreement to extend the period during which you may exercise the Stock Option. Section 3.3(c) of the Stock Option Agreement is amended to read as follows:

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