0001564590-16-028797 Sample Contracts

October 21, 2016 Re:Amended and Restated Employment Agreement Dear Po-Shun:
Separation Agreement and Release • November 10th, 2016 • Proteostasis Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts
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October 21, 2016 Re:Amended and Restated Employment Agreement Dear Meenu:
Offer Letter Agreement • November 10th, 2016 • Proteostasis Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

The Board of Directors has recently reviewed the terms and conditions of your employment and is pleased to provide this amended and restated letter agreement (the “Agreement”) modifying the terms of your employment in your continuing role as President and Chief Executive Officer of Proteostasis Therapeutics, Inc. (“Proteostasis” or the “Company”). This Agreement amends, restates, and supersedes in its entirety the letter agreement dated April 4, 2014 between you and the Company (the “Offer Letter Agreement”) and the letter agreement dated March 10, 2016. This Agreement is effective as of the date hereof.

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