0001564590-17-014760 Sample Contracts

FIRST AMENDMENT TO THE CO-PROMOTION AGREEMENT
Co-Promotion Agreement • August 2nd, 2017 • Amarin Corp Plc\uk • Pharmaceutical preparations

This First Amendment (the “Amendment”) to the March 31, 2014 Co-Promotion Agreement is entered into and effective as of July 25, 2017, by and among Amarin Pharmaceuticals Ireland Limited, a company organized under the laws of Ireland (registered number 408912) with offices at 2 Pembroke House Upper Pembroke Street 28-32, Dublin 2, Ireland (“Amarin Ireland”), and Amarin Pharma, Inc., a Delaware corporation with offices at 1430 Route 206 North, Suite 101, Bedminster, NJ 07921 (“Amarin Pharma”, and collectively with Amarin Ireland, “Amarin”), on the one hand, and Kowa Pharmaceuticals America, Inc., a Delaware corporation with offices at 530 Industrial Park Blvd, Montgomery, AL 36117 (“Kowa”), on the other hand (collectively, the “Parties”).

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