0001564590-17-016546 Sample Contracts

Re: Registration Rights
Registration Rights Agreement • August 8th, 2017 • HTG Molecular Diagnostics, Inc • Laboratory analytical instruments • Delaware

This letter agreement (this “Agreement”) will serve to memorialize the understanding between HTG Molecular Diagnostics, Inc. (the “Company”) and NOVO A/S (“Holder”) with respect to the Registrable Securities held by Holder. Capitalized terms used and not defined herein have the meanings ascribed to such terms in that certain Amended and Restated Investor Rights Agreement, entered into December 22, 2014, by and between the Company, the Holder and the other parties named therein, as amended (the “IRA”).

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First Amendment to Master Assay Development, Commercialization and Manufacturing Agreement
Master Assay Development, Commercialization and Manufacturing Agreement • August 8th, 2017 • HTG Molecular Diagnostics, Inc • Laboratory analytical instruments

First Amendment to Master Assay Development, Commercialization and Manufacturing Agreement (“Amendment”), dated June 14, 2017, is by and between HTG Molecular Diagnostics, Inc., a corporation organized under the laws of the State of Delaware, U.S., with a place of business at 3430 E. Global Loop, Tucson, AZ 85706 and QIAGEN Manchester Limited, a corporation organized under the laws of the United Kingdom, with a place of business at Skelton House, Lloyd Street North, Manchester, UK.

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