0001564590-18-004398 Sample Contracts

SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • March 5th, 2018 • Cytokinetics Inc • Pharmaceutical preparations • California

THIS SECOND AMENDMENT to Loan and Security Agreement (this “Amendment”) is entered into as of October 27, 2017, by and between OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 of the Loan Agreement (as defined below) or otherwise party thereto from time to time (each a “Lender” and collectively, the “Lenders”) including Oxford in its capacity as a Lender and SILICON VALLEY BANK, a California corporation with an office located at 3003 Tasman Drive, Santa Clara, CA 95054 (“Bank” or “SVB”) (each a “Lender” and collectively, the “Lenders”), and CYTOKINETICS, INCORPORATED, a Delaware corporation with offices located at 280 East Grand Avenue, South San Francisco, CA 94080 (“Borrower”).

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FIFTH AMENDMENT TO LEASE
Lease • March 5th, 2018 • Cytokinetics Inc • Pharmaceutical preparations

This FIFTH AMENDMENT TO LEASE (this "Fifth Amendment") is made and entered into as of the 18th day of December, 2017, by and between BRITANNIA POINTE GRAND LIMITED PARTNERSHIP, a Delaware limited partnership ("Landlord"), and CYTOKINETICS, INC., a Delaware corporation ("Tenant").

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