0001564590-18-009692 Sample Contracts

LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • April 30th, 2018 • Zai Lab LTD • Pharmaceutical preparations • New York

This License and Collaboration Agreement (this “Agreement”) is made as of December 19, 2017 (the “Effective Date”), by and between Five Prime Therapeutics, Inc., a Delaware corporation (“Five Prime”), having a place of business at 111 Oyster Point Boulevard, South San Francisco, California 94080, USA, and Zai Lab (Shanghai) Co., Ltd., a limited company organized under the laws of P.R. of China (“Zai”), having a place of business at 4560 Jinke Rd, Bldg. 1, 4/F, Pudong, Shanghai, China, 201210. Five Prime and Zai are referred to in this Agreement individually as a “Party” and collectively as the “Parties.”

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THIRD AMENDED AND RESTATED FOUNDER EMPLOYMENT AGREEMENT
Founder Employment Agreement • April 30th, 2018 • Zai Lab LTD • Pharmaceutical preparations • New York

THIS THIRD AMENDED AND RESTATED FOUNDER EMPLOYMENT AGREEMENT (“Agreement”) is made and entered into as of November 10, 2017 (the “Effective Date”), by and between Zai Lab Limited, a limited company incorporated under the laws of the Cayman Islands (the “Company”), and Samantha (Ying) Du, an individual (the “Founder”).

EMPLOYMENT AGREEMENT
Employment Agreement • April 30th, 2018 • Zai Lab LTD • Pharmaceutical preparations • Hong Kong

THIS EMPLOYMENT AGREEMENT (“Agreement”) is made and entered into on March 2, 2018 (the “Effective Date”), by and between Zai Lab (Hong Kong) Ltd., a limited company incorporated under the laws of Hong Kong whose registered office is at Room 1902, 19/F, Lee Garden One, 33 Hysan Avenue, Causeway Bay, Hong Kong (the “Company”), and William Ki Chul Cho, an individual (the “Employee”) whose correspondence address is XXX and whose US passport number is XXX.

Amendment to Collaboration, Development and License Agreement
Development and License Agreement • April 30th, 2018 • Zai Lab LTD • Pharmaceutical preparations • New York

THIS AMENDMENT TO COLLABORATION, DEVELOPMENT AND LICENSE AGREEMENT (the “Amendment”) is made and entered into as of February 26, 2018 by and among Tesaro, Inc., a Delaware corporation (“Tesaro Inc.”), Tesaro Development Ltd., a Bermuda corporation (“TSRO Ltd.” and together with Tesaro Inc., “Tesaro”), and Zai Lab (Shanghai) Co., Ltd., a limited liability company organized under the laws of the People’s Republic of China (“Zai” and together with Tesaro, the “Parties”).

December 11, 2017 Samantha (Ying) Du c/o Zai Lab Limited 4560 jinke Road, Bldg. 1,4F Pudong, Shanghai, 201210, China Dear Samantha:
Letter Agreement • April 30th, 2018 • Zai Lab LTD • Pharmaceutical preparations

This letter agreement (the “Agreement”) shall serve to supplement the terms and conditions of that certain Third Amended and Restated Founder Employment Agreement between you and Zai Lab Limited (the “Company”) dated November 10, 2017 (the “Founder Agreement”).

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