0001564590-18-015497 Sample Contracts

to Loan and security agreement
Loan and Security Agreement • June 13th, 2018 • Xenon Pharmaceuticals Inc. • Pharmaceutical preparations

This First Loan Modification Amendment to Loan and Security Agreement (this “Amendment”) is entered into this 12th day of June, 2018, by and between (A) SILICON VALLEY BANK, a California corporation with a loan production office located at 505 Howard Street, 3rd Floor, San Francisco, California, 94105 (“Bank”) and (B) XENON PHARMACEUTICALS INC., a corporation continued under the laws of Canada with the registered address 745 Thurlow Street, Suite 2400, Vancouver, British Columbia, V6E 0C5, Canada (the “Canadian Borrower”) and XENON PHARMACEUTICALS USA INC., a corporation organized under the laws of the State of Delaware (the “U.S. Borrower”, and together with the Canadian Borrower herein, jointly and severally, individually and collectively, “Borrower”).

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