0001564590-19-003324 Sample Contracts

RIVERSIDE TECHNOLOGY CENTER THIRD LEASE AMENDMENT TO THE LEASE BETWEEN RIVERTECH ASSOCIATES II LLC AND ULTRAGENYX PHARMACEUTICAL INC.
Third Lease Amendment • February 20th, 2019 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations • Massachusetts

This Third Lease Amendment (the “Third Lease Amendment”) entered into effective as the 31st day of December, 2018 by and between Rivertech Associates II LLC, a Massachusetts limited liability company with a principal address c/o The Abbey Group, 177 Huntington Avenue 24th Floor Boston, Massachusetts 02115 (herein, the “Lessor”), and Ultragenyx Pharmaceutical, Inc. a Delaware corporation (as it is the successor and assignee from Dimension Therapeutics, Inc.), with a business address of 60 Leveroni Court, Novato, California 94949 (herein the “Lessee”); with respect to a certain Lease dated March 11, 2014 (the “Original Lease”) for certain office and laboratory space in the building at 840 Memorial Drive Cambridge, Massachusetts (the “Building”); as amended by a certain First Lease Amendment dated October 22, 2014 (the “First Amendment”), and a Second Lease Amendment dated April 28, 2017 (the “Second Amendment”); said Original Lease, First Amendment and Second Amendment being collectively

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