0001564590-19-006771 Sample Contracts

Amended and Restated Patent License Agreement Agreement No. PM1401501
Patent License Agreement • March 7th, 2019 • Aeglea BioTherapeutics, Inc. • Pharmaceutical preparations • Texas

This Amended and Restated Patent License Agreement (“Patent License Agreement”) is between the Licensor and the Licensee identified below (collectively, “Parties”, or singly, “Party”).

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AMENDMENT NO. 1 TO AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • March 7th, 2019 • Aeglea BioTherapeutics, Inc. • Pharmaceutical preparations • Delaware

This Amendment No. 1 to Amended and Restated Investor Rights Agreement (this “Amendment”) is entered into as of December 4, 2018 by the undersigned parties to that certain Amended and Restated Investor Rights Agreement, dated as of March 10, 2015 (the “Rights Agreement”), by and among Aeglea BioTherapeutics, Inc., a Delaware corporation (the “Company”) and the Investors. Capitalized terms used but not defined herein shall have the meanings ascribed to them in the Rights Agreement.

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