0001564590-20-009167 Sample Contracts

March 5, 2020 Ms. Shalini Sharp Executive Vice President and Chief Financial Officer Ultragenyx Pharmaceutical Inc. Novato, CA 94949 Re: Transition Dear Shalini:
Confidential Transition Agreement and General Release • March 6th, 2020 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations • California

You have announced your intention to retire from your position of Executive Vice President and Chief Financial Officer of Ultragenyx Pharmaceutical Inc. (the “Company”) on the date that is the earlier of (i) the date your successor Chief Financial Officer of the Company commences employment and (ii) September 2, 2020 (such date, the “Officer Resignation Date”).

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