0001564590-20-010810 Sample Contracts

THIRD AMENDMENT TO SECOND AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations • California

THIS THIRD AMENDMENT to Second Amended and Restated Loan and Security Agreement (this “Amendment”) is entered into as of October 18, 2019, by and among SILICON VALLEY BANK, a California corporation (“Bank”), as collateral agent (in such capacity, “Collateral Agent”), Bank in its capacity as a Lender, and the other Lenders party to that certain Second Amended and Restated Loan and Security Agreement dated as of May 14, 2018 (as the same may from time to time be amended, modified, supplemented or restated, including by that certain Consent and First Amendment to Second Amended and Restated Loan and Security Agreement dated as of July 3, 2019 and that certain Consent and Second Amendment to Second Amended and Restated Loan and Security Agreement dated as of August 29, 2019, collectively, the “Loan Agreement”) (together with Bank, each a “Lender” and collectively, the “Lenders”), and CLEARSIDE BIOMEDICAL, INC., a Delaware corporation (“Borrower”).

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April 24, 2019 Daniel H. White
Clearside Biomedical, Inc. • March 13th, 2020 • Pharmaceutical preparations • Georgia
RELEASE AND SETTLEMENT AGREEMENT
Release and Settlement Agreement • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations • California

This Release and Settlement Agreement (“Agreement”) is entered into by and between Clearside Biomedical, Inc., a Delaware corporation (the “Company”), and Brion Raymond (“Employee”) (collectively, the “Parties”).

OPTION AND LICENSE AGREEMENT BY AND BETWEEN REGENXBIO INC. AND CLEARSIDE BIOMEDICAL, INC. August 29, 2019
Option and License Agreement • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations • Delaware

This Option and License Agreement (the “Agreement”) is entered into as of August 29, 2019 (the “Effective Date”), by and between Clearside Biomedical, Inc., a Delaware corporation with a place of business at 900 North Point Parkway, Suite 200, Alpharetta, Georgia 30004 (“Clearside”) and REGENXBIO Inc., a Delaware corporation with a place of business at 9600 Blackwell Road, Suite 210, Rockville, Maryland 20850 (“REGENXBIO”). Clearside and REGENXBIO may each be referred to herein individually as a “Party” and collectively as the “Parties.”

LICENSE AGREEMENT
License Agreement • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations

This License Agreement (this “Agreement”) is made as of October 22, 2019 (the “Effective Date”), by and between Clearside Biomedical, Inc., a Delaware corporation having a place of business at 900 North Point Parkway, Suite 200, Alpharetta, GA 30005, United States of America (“Clearside”), and Bausch Health Ireland Limited, an Irish company having an office at 3013 Lake Drive, Citywest Business Campus, Dublin, Ireland (“Bausch Health”). Clearside and Bausch Health are referred to in this Agreement individually as a “Party” and collectively as the “Parties.”

CONSENT AND FOURTH AMENDMENT TO SECOND AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT
Consent And • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations • California

THIS CONSENT AND FOURTH AMENDMENT to Second Amended and Restated Loan and Security Agreement (this “Amendment”) is entered into as of October 22, 2019, by and among SILICON VALLEY BANK, a California corporation (“Bank”), as collateral agent (in such capacity, “Collateral Agent”), Bank in its capacity as a Lender, and the other Lenders party to that certain Second Amended and Restated Loan and Security Agreement dated as of May 14, 2018 (as the same may from time to time be amended, modified, supplemented or restated, including without limitation by that certain Consent and First Amendment to Second Amended and Restated Loan and Security Agreement dated as of July 3, 2019, that certain Consent and Second Amendment to Second Amended and Restated Loan and Security Agreement dated as of August 29, 2019, and that certain Third Amendment to Second Amended and Restated Loan and Security Agreement dated as of October 18, 2019, collectively, the “Loan Agreement”) (together with Bank, each a “Le

CONSULTING AND INDEPENDENT CONTRACTOR AGREEMENT
Consulting and Independent Contractor Agreement • March 13th, 2020 • Clearside Biomedical, Inc. • Pharmaceutical preparations • Georgia

THIS CONSULTING AND INDEPENDENT CONTRACTOR AGREEMENT (“Agreement”) is made by and between Clearside Biomedical, Inc., a Delaware corporation (the “Company” or “Clearside”), and Brion Raymond (“Consultant”) (hereinafter collectively “the parties”) and entered into as of the date of execution by both parties (the “Effective Date”).

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