0001564590-20-036954 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 5th, 2020 • G1 Therapeutics, Inc. • Pharmaceutical preparations • California

THIS LOAN AND SECURITY AGREEMENT is made and dated as of May 29, 2020 and is entered into by and among G1 THERAPEUTICS, INC., a Delaware corporation, and each of its Subsidiaries (hereinafter collectively referred to as the “Borrower”), the several banks and other financial institutions or entities from time to time parties to this Agreement (collectively, referred to as the “Lenders”) and HERCULES CAPITAL, INC., a Maryland corporation, in its capacity as administrative agent and collateral agent for itself and the Lenders (in such capacity, the “Agent”).

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Scientific, Clinical, and Regulatory Advisor AGREEMENT
Scientific, Clinical, and Regulatory Advisor Agreement • August 5th, 2020 • G1 Therapeutics, Inc. • Pharmaceutical preparations • North Carolina

This SCIENTIFIC, CLINICAL, AND REGULATORY ADVISOR AGREEMENT (the ''Agreement"), is effective as of July 1, 2020 (the "Effective Date"), by and between G1 Therapeutics, Inc., a Delaware corporation (the "Company"), and you. This Agreement replaces that certain Advisory Board Member Agreement, effective July 1, 2018, by and between the Company and you, which expired by its terms on June 30, 2020.

CO-PROMOTION AGREEMENT by and between G1 THERAPEUTICS, INC. and BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. June 29, 2020
Co-Promotion Agreement • August 5th, 2020 • G1 Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Co-Promotion Agreement (“Agreement”) is entered into and dated as of June 29, 2020 (the “Effective Date”) by and between G1 Therapeutics, Inc., a Delaware corporation, with offices at 700 Park Offices, Research Triangle Park, NC 27709 (“G1”), and Boehringer Ingelheim Pharmaceuticals, Inc., a Delaware corporation, with offices at 900 Ridgebury Road, Ridgefield, CT 06877 (“BI”). G1 and BI are each referred to individually as a “Party” and together as the “Parties”.

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