INCREMENTAL AMENDMENTIncremental Amendment • November 2nd, 2020 • Horizon Therapeutics Public LTD Co • Pharmaceutical preparations
This INCREMENTAL AMENDMENT AND LENDER JOINDER AGREEMENT (this “Agreement”), dated as of August 17, 2020, is entered into by and among JPMORGAN CHASE BANK, N.A., as an Incremental Revolving Lender and as an Issuing Bank (in such capacities, the “New Lender”), HORIZON THERAPEUTICS USA, INC., a Delaware corporation (the “Borrower”), and CITIBANK, N.A., as Administrative Agent (in such capacity, together with its successors and assigns, “Administrative Agent”). Capitalized terms used herein and not otherwise defined shall have the meanings set forth in the Credit Agreement (as defined below).
API SUPPLY AGREEMENTApi Supply Agreement • November 2nd, 2020 • Horizon Therapeutics Public LTD Co • Pharmaceutical preparations • New York
This API Supply Agreement (“Agreement”) is made as of the 3rd day of November, 2010 (“Effective Date”), by and between Raptor Therapeutics, Inc., a Delaware Corporation, with a place of business at 9 Commercial Boulevard, Suite 200, Novato, California 94949, U.S.A. (“RAPTOR”), and Cambrex Profarmaco Milano, Via Cucchiari 17, 20155 Milan, Italy (“CAMBREX”). RAPTOR and CAMBREX may be referred to individually as a “Party” or collectively as the “Parties.”
AMENDMENT NO. 3 TO COMMERCIAL SUPPLY AGREEMENTCommercial Supply Agreement • November 2nd, 2020 • Horizon Therapeutics Public LTD Co • Pharmaceutical preparations
This Amendment No. 3 (the “Amendment”) to the Commercial Supply Agreement by and between Horizon Therapeutics Ireland DAC, formerly known as Horizon Pharma Ireland Limited (“Customer”) and AGC Biologics A/S, formerly known as CMC Biologics A/S (“AGC”) is dated as of July 31, 2020 (“Amendment Effective Date”).
CONFIDENTIAL DEVELOPMENT AND MANUFACTURING SERVICES AGREEMENTDevelopment and Manufacturing Services Agreement • November 2nd, 2020 • Horizon Therapeutics Public LTD Co • Pharmaceutical preparations • New York
This agreement is made as of June 10, 2015 (“Effective Date”) between CMC Biologics A/S, a , duly incorporated under the laws of the Kingdom of Denmark (“CMC”), and River Vision Development Corp., a Delaware Corporation (“Customer”).
