0001564590-21-014593 Sample Contracts

FIRST Amendment
Loan and Security Agreement • March 22nd, 2021 • Spruce Biosciences, Inc. • Pharmaceutical preparations

This First Amendment to Loan and Security Agreement (this “Amendment”) is entered into as of March 19, 2021, by and between Silicon Valley Bank (“Bank”) and Spruce Biosciences, Inc., a Delaware corporation (“Borrower”), whose address is 2001 Junipero Serra Blvd., Suite 640, Daly City, CA 94014.

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