0001564590-21-015271 Sample Contracts

AMENDMENT NO. 2 TO ASSET PURCHASE AGREEMENT
Asset Purchase Agreement • March 25th, 2021 • Fusion Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Delaware

This Amendment No. 2 to Asset Purchase Agreement (this “Second Amendment”), effective as of February 8, 2021 (the “Second Amendment Effective Date”), is entered into by and among Fusion Pharmaceuticals, Inc., a Canadian federal corporation with its principal place of business at 270 Longwood Road S., Hamilton, Ontario L8P 0A6 (“Purchaser”); Rainier Therapeutics, Inc., a Delaware corporation with its principal place of business at 500 Mercer Street, Suite C202, Seattle, Washington 98109 (“Seller”); and Fortis Advisors LLC, a Delaware limited liability company solely in its capacity as the representative for Seller for certain obligations (“Seller Representative”). Purchaser, Seller, and Seller Representative are referred to herein individually as a “Party” and collectively, as the “Parties”.

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AMENDMENT No. 1 EMPLOYMENT AGREEMENT
Employment Agreement • March 25th, 2021 • Fusion Pharmaceuticals Inc. • Biological products, (no disgnostic substances)

This Amendment No. 1 (the “Amendment”) to that certain Employment Agreement, dated as of June 25, 2020 (“Agreement”) is made between Fusion Pharmaceuticals Inc. (the “Company”), and Eric Burak (the “Executive”) and is effective as of February 19, 2021 (the “Effective Date”).

AMENDMENT No. 1 EMPLOYMENT AGREEMENT
Employment Agreement • March 25th, 2021 • Fusion Pharmaceuticals Inc. • Biological products, (no disgnostic substances)

This Amendment No. 1 (the “Amendment”) to that certain Employment Agreement, dated as of June 25, 2020 (“Agreement”) is made between Fusion Pharmaceuticals Inc. (the “Company”), and John Valliant (the “Executive”) and is effective as of February 19, 2021 (the “Effective Date”).

TWO INTERNATIONAL PLACE Boston, Massachusetts FIRST AMENDMENT TO LEASE Fusion Pharmaceuticals US Inc.
Lease • March 25th, 2021 • Fusion Pharmaceuticals Inc. • Biological products, (no disgnostic substances) • Massachusetts

First Amendment to Lease (the “Amendment”) dated as of March 16, 2021, between Fort Hill Square 2 Owner LLC, a Delaware limited liability company (“Landlord”), and Fusion Pharmaceuticals US Inc., a Delaware corporation (“Tenant”).

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