0001626199-19-000010 Sample Contracts

LICENSE AND RESEARCH AGREEMENT AMENDMENT NO. 2
License and Research Agreement • March 18th, 2019 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations

This License and Research Agreement Amendment No. 2 (this “Amendment No. 2”) is made effective as of October 17, 2018 (the “Amendment Effective Date”) by and between AIS Operating Co., Inc., f/k/a Alpine Immune Sciences, Inc., a Delaware corporation (“Alpine”), and Kite Pharma, Inc., a Delaware corporation (“Kite”), with reference to the following facts:

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