0001626199-22-000032 Sample Contracts

STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • March 17th, 2022 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • New York

This Stock Purchase Agreement (this “Agreement”) is dated as of December 15, 2021, by and between Alpine Immune Sciences, Inc., a Delaware corporation (the “Company”), and Horizon Therapeutics Ireland DAC, an Irish company (the “Purchaser”).

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SEPARATION AGREEMENT AND RELEASE
Separation Agreement and Release • March 17th, 2022 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • California

This Separation Agreement and Release (“Agreement”) is made by and between Zelanna Goldberg (“Employee”) and Alpine Immune Sciences, Inc. (the “Company”) (collectively referred to as the “Parties” or individually referred to as a “Party”).

CERTAIN INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH NOT MATERIAL AND WOULD LIKELY CAUSE COMPETITIVE HARM TO THE REGISTRANT IF PUBLICLY DISCLOSED. OMISSIONS ARE DESIGNATED AS [***]. LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • March 17th, 2022 • Alpine Immune Sciences, Inc. • Pharmaceutical preparations • New York

This LICENSE AND COLLABORATION AGREEMENT (the “Agreement”) is entered into as of December 15, 2021 (the “Effective Date”) by and between Horizon Therapeutics Ireland DAC, a company formed under the laws of Ireland (“Horizon”), and Alpine Immune Sciences, Inc., a Delaware corporation (“Alpine”). Alpine and Horizon are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

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