0001628280-16-020766 Sample Contracts

ACKNOWLEDGMENT OF COMMENCEMENT DATE
Arbutus Biopharma Corp • November 3rd, 2016 • Pharmaceutical preparations

This ACKNOWLEDGMENT OF COMMENCEMENT DATE is made as of this 7 day of October, 2016, between ARE-PA REGION NO. 7, LLC, a Delaware limited liability company (“Landlord”), and ARBUTUS BIOPHARMA, INC., a Delaware corporation (“Tenant”), and is attached to and made a part of the Lease Agreement dated as of August 9, 2016 (“Lease”), by and between Landlord and Tenant. Any initially capitalized terms used but not defined herein shall have the meanings given them in the Lease.

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FIRST AMENDMENT TO LEASE AGREEMENT
Lease Agreement • November 3rd, 2016 • Arbutus Biopharma Corp • Pharmaceutical preparations

This FIRST AMENDMENT TO LEASE AGREEMENT (“this First Amendment”) is dated as of October 7, 2016 (“Effective Date”), by and between ARE-PA REGION NO. 7, LLC, a Delaware limited liability company, having an address at 385 E. Colorado Boulevard, Suite 299, Pasadena, California 91101 (“Landlord”), and ARBUTUS BIOPHARMA, INC., a Delaware corporation, having an address at 100-8900 Glenlyon Parkway, Burnaby, British Columbia, Canada V5J 5J8 (“Tenant”).

Re: Termination and Severance Agreement
Arbutus Biopharma Corp • November 3rd, 2016 • Pharmaceutical preparations

Further to our recent discussions, set out below are the terms we have agreed upon regarding the ending of your employment with Arbutus Biopharma Corporation (the “Company”). Please review the letter and enclosure carefully and seek any advice you deem appropriate.

LEASE AGREEMENT
Lease Agreement • November 3rd, 2016 • Arbutus Biopharma Corp • Pharmaceutical preparations

THIS LEASE AGREEMENT (“this Lease”) is made as of this 9th day of August, 2016, between ARE-PA REGION NO. 7, LLC, a Delaware limited liability company (“Landlord”), and ARBUTUS BIOPHARMA, INC., a Delaware corporation (“Tenant”).

Re: Termination and Severance Agreement
Arbutus Biopharma Corp • November 3rd, 2016 • Pharmaceutical preparations

Further to our recent discussions, this letter confirms the termination of your employment with Arbutus Biopharma Corporation (the “Company”) effective September 30, 2016. You will receive any earned but unpaid Base Salary and any accrued and unused vacation time as of this date.

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