0001628280-20-012332 Sample Contracts

ADVERUM BIOTECHNOLOGIES, INC. AMENDED AND RESTATED CHANGE IN CONTROL AND SEVERANCE AGREEMENT
Change in Control and Severance Agreement • August 10th, 2020 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances) • California

This Amended and Restated Change in Control and Severance Agreement (the “Agreement”) is made and entered into by and between Leone Patterson (“Executive”) and Adverum Biotechnologies, Inc. (the “Company”), effective as of June 23, 2020 (the “Effective Time”), and shall supersede and replace the terms set forth in the Amended and Restated Change in Control and Severance Agreement executed by the parties on June 11, 2020 (the “Prior Severance Agreement”).

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Re: Amended and Restated Employment Terms
Adverum Biotechnologies, Inc. • August 10th, 2020 • Biological products, (no disgnostic substances) • California

Effective at the Effective Time (as defined below), this letter agreement (the “Agreement”) sets forth the amended and restated terms of your employment with Adverum Biotechnologies, Inc. (the “Company”) and supersedes and replaces the terms set forth in your earlier amended and restated offer letter from the Company dated October 24, 2018 (the “2018 Offer Letter”).

Re: Employment Terms
Letter Agreement • August 10th, 2020 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances) • California

This letter agreement (the “Agreement”) memorializes the employment terms for your anticipated hire by Adverum Biotechnologies, Inc. (the “Company”) in the position of Chief Executive Officer. These terms will become effective on June 15, 2020 or at a later date determined by mutual agreement (as applicable, the “Hire Date”).

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