0001628280-21-009717 Sample Contracts

VIA HAND DELIVERY Michael J. Kaufman C/O Mersana Therapeutics, Inc. Cambridge, MA 02139 Dear Michael:
Employment Agreement • May 10th, 2021 • Mersana Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

This letter agreement (this “Agreement”) amends and restates in its entirety, as of the date set forth above, the offer letter between you and Mersana Therapeutics, Inc. (the “Company”) dated December 14, 2015. In consideration of your continued employment by the Company, and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, you and the Company agree as follows:

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VIA E-MAIL Arvin S. Yang, MD, PHD c/o Mersana Therapeutics, Inc. 840 Memorial Drive Cambridge, MA 02139 Dear Arvin:
Employment Agreement • May 10th, 2021 • Mersana Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts
RIVERSIDE TECHNOLOGY CENTER EIGHTH LEASE MODIFICATION AGREEMENT TO THE LEASE BETWEEN RIVERTECH ASSOCIATES II LLC AND MERSANA THERAPEUTICS, INC.
Lease Modification Agreement • May 10th, 2021 • Mersana Therapeutics, Inc. • Pharmaceutical preparations • Massachusetts

This Eighth Lease Modification Agreement entered into this 25th day of March, 2021 (the “Eighth Lease Amendment”) by and between Rivertech Associates II LLC, a Massachusetts limited liability company with a principal address c/o The Abbey Group, 177 Huntington Avenue 24th Floor Boston, Massachusetts 02115, (the “Lessor”); and Mersana Therapeutics, Inc., with a business address at 840 Memorial Drive Cambridge, Massachusetts (the “Lessee”); relative to a certain Lease between Lessor and Lessee dated February 24, 2009, as modified by a certain Lease Extension and Modification Agreement dated July 27, 2010 (the “First Lease Amendment”); as further modified by a Second Lease Extension and Modification Agreement dated May 29, 2012 (the “Second Lease Amendment”); as further modified by a Third Lease Extension and Modification Agreement dated February 7, 2013 (the “Third Lease Amendment”); as further modified by a Fourth Lease Extension and Modification Agreement dated April 30, 2014 (the “Fou

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