0001628280-24-019990 Sample Contracts

Second Amendment to Commercial Lease
Commercial Lease • May 2nd, 2024 • Ardelyx, Inc. • Pharmaceutical preparations

The Parties hereto, Prospect Fifth Ave LLC, (“Landlord”) and Ardelyx, Inc. ( “Tenant”) are Parties under a certain Commercial Lease dated December 30, 2020 and a First Amendment of Lease dated April 9, 2021 (jointly the “Lease Agreement”) for approximately 12,864 rentable square feet on the second (2nd) and third (3rd) floors at 400 Fifth Avenue, Waltham, MA (“Building”), Suites 210 and 300, hereby agree as follows:

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Third Amendment to Commercial Lease
Commercial Lease • May 2nd, 2024 • Ardelyx, Inc. • Pharmaceutical preparations

The Parties hereto, Prospect Fifth Ave LLC, (“Landlord”) and Ardelyx, Inc. ( “Tenant”) are Parties under a certain Commercial Lease dated December 30, 2020, a Commencement Date Agreement dated March 18, 2021, a First Amendment of Lease dated April 9, 2021, and a Second Amendment to Commercial Lease dated August 18, 2023 (collectively the “Lease Agreement”) for approximately 17,111 rentable square feet on the second (2nd) and third (3rd) floors at 400 Fifth Avenue, Waltham, MA (“Building”), Suites 210, 300, and 310, hereby agree as follows:

February 13, 2024
Ardelyx, Inc. • May 2nd, 2024 • Pharmaceutical preparations

On behalf of Ardelyx (the “Company”), I am pleased to offer you employment in the exempt position of Executive Vice President, Corporate Development and Strategy, reporting to Mike Raab, President and Chief Executive Officer. In this role, you will be a member of the Executive Leadership Team. You will be primarily located in Chicago, Illinois, with travel as necessary. If you accept this offer, you and the Company will enter into a Change in Control Severance Agreement that will further define some of the provisions set forth in this offer letter (the “Severance Agreement”).

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