0001714899-24-000075 Sample Contracts

DENALI THERAPEUTICS INC. SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • February 27th, 2024 • Denali Therapeutics Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (the “Agreement”) is made as of February 27, 2024 (the “Effective Date”), by and among Denali Therapeutics Inc., a Delaware corporation (the “Company”), and each of the purchasers whose names and addresses are set forth on the signature pages hereof (each, a “Purchaser” and, collectively, the “Purchasers”).

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NOMINATING AGREEMENT
Nominating Agreement • February 27th, 2024 • Denali Therapeutics Inc. • Biological products, (no disgnostic substances) • Delaware

THIS NOMINATING AGREEMENT (this “Agreement”), dated as of February [29], 2024, is by and between Denali Therapeutics Inc., a Delaware corporation (the “Company”) and Baker Brothers Life Sciences, L.P. and 667, L.P. (collectively, the “Investor”).

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