0001937653-22-000009 Sample Contracts

PREFERRED SHARES RIGHTS AGREEMENT
Preferred Shares Rights Agreement • November 8th, 2022 • Zymeworks Inc. • Pharmaceutical preparations • Delaware

This AMENDMENT NO. 1 TO THE PREFERRED SHARES RIGHTS AGREEMENT (this “Amendment”) is dated as of October 12, 2022 (the “Effective Date”), and amends the Preferred Shares Rights Agreement, dated as of June 9, 2022 (the “Rights Agreement”), by and between Zymeworks Inc., a corporation continued under the Business Corporations Act (British Columbia) (the “Company”), and Computershare Trust Company, N.A., a United States federally chartered trust company, as rights agent (the “Rights Agent”). Capitalized terms used in this Amendment and not otherwise defined have the meaning given to them in the Rights Agreement.

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