EXHIBIT 10.2.1 AMENDMENT TO EMPLOYMENT AGREEMENT THIS AMENDMENT TO THE EMPLOYMENT AGREEMENT DATED February 5, 1996 ("the Amendment") is made and entered into this 1st day of February 2001 by and between SeraCare, Inc., a Delaware Corporation (referred...

                                                                  EXHIBIT 10.2.1

                       AMENDMENT TO EMPLOYMENT AGREEMENT

     THIS AMENDMENT TO THE EMPLOYMENT AGREEMENT DATED February 5, 1996 ("the
Amendment") is made and entered into this 1st day of February 2001 by and
between SeraCare, Inc., a Delaware Corporation  (referred herein as the
"Corporation") and Xxxxx X. Xxxxx  (the "Employee").

WHEREAS, the Corporation previously entered into an employment agreement on
February 5, 1996, (the "Employment Agreement");

AND WHEREAS the term of the Employment Agreement was previously extended  by the
Board of Directors  through February 5, 2002;

AND WHEREAS, the Corporation hereby wishes to amend the employment again;

AND WHEREAS the Employee wishes to have the employment agreement amended as
specified herein;

Now Therefore, the following extension and amendments are hereby agreed to by
both the Corporation and the Employee:

1.   The Term of the agreement has been extended through February 5, 2002.
2.   Effective February 1, 2001, the base annual compensation is hereby adjusted
     to be $300,000 per year plus an auto allowance of $750.00 per month.
3.   Employee shall receive 200,000 options with an exercise price of $3.25.
     Such options shall all have 7 year cliff vesting with accelerated vesting
     as follows:
          100,000 options will have accelerated vesting over two years beginning
               with satisfactory achievement of the fiscal year 2002 business
               plan, half upon achievement of plan, other half 1 year later.

          100,000 options will have accelerated vesting on the following
          schedule;
               10,000 options will vest immediately at the end of each month
               that the closing price of the Company's stock is $6.50 or greater
               for at least 10 trading days during the month.

     All 200,000 options shall be accelerated in the event of a change of
     control.

All other terms, conditions and provisions of the Employment Agreement shall
remain effective throughout the term of this Amendment.

I hereby certify that the above amendment was adopted by unanimous vote of the
Board of Directors on January 12, 2001.

                                         Hereby certified

                                         ____________________
                                         Xxxxx X. Xxxxxxx
                                         Corporate Secretary