Internal standard definition

Internal standard means an analyte added to calibra- tion standards, blanks, quality control and analytical samples as a reference for evaluating and controlling the precision and bias of an analytical test. Responses of internal standards are used to adjust the quantities of analytes reported in tests that employ the standards.
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Internal standard means a known amount of standard added to a test portion of a sample as a reference for evaluating and controlling the precision and bias of the applied analytical method. (NELAC)
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Internal standard means a known concentration of standard added to a sample or quality control sample as a reference for evaluating and controlling the precision and bias of the analytical method.
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Examples of Internal standard in a sentence

  • Internal standard variations were trended and used as part of the verifications of result validity.

  • See Section 6.3.1 for QC instructions):o Internal standard working solution - THCA-D3, 1 μg/mL in methanol.o Drug standard working solution – THCA 1.5 μg/mL in methanol.o Drug control working solution – THCA 1.5 μg/mL in methanol.o THCA glucuronide control working solution – THCA glucuronide 1 μg/mL in methanol.

  • Internal standard operating procedures (SOPs) may be referenced provided they are available for audit review.

  • See Section 6.3.1 for QC instructions):o Internal standard working solution – 2 µg/mL nordiazepam-D5, oxazepam- D5, diazepam-D5, lorazepam-D4, temazepam-D5, clonazepam-D4, alprazolam- D5, triazolam-D4 in methanol.

  • Internal standard areas should be consistent with the response found in the associated calibrators and positive controls.

  • Internal standard performance criteria insure that the GC/MS sensitivity and response are stable during every sample analysis.

  • Internal standard areas and retention time shifts: Internal standard area counts in each sample must not vary by more than a factor of 2 from the associated 12-hour standard.

  • Internal standard recovery as measured by peak area shall be monitored for calibrators, quality controls, and case specimens within a batch on the Calibration Batch (calibrators and quality controls) and Data Summary (case samples) respectfully.

  • Internal standard ritonavir (200 nM) was prepared in acetonitirile.

  • Internal standard (IS) atenolol solution was pre- pared at concentration of 50 μg ml-1.


More Definitions of Internal standard

Internal standard means a standard specification prepared for local use by a local administration, a Government department, a statutory corporation or any other person or association below thenational level level;
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Internal standard means a known concentration of an analyte added to calibration standards, blanks, laboratory control samples, matrix spikes, matrix spike duplicates, replicate samples, and environmental samples as a reference for evaluating and controlling the precision and bias of a method.
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Internal standard means a written document maintained by each Lead Buyer and Lead Seller, that sets forth its policies, procedures, and/or guidelines with respect to online advertising and marketing.
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Internal standard means a standard specification prepared for local use by a local administration, a Government department, a statutory corporation or any other person or association below the
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Internal standard means a chemical substance that is similar, but not identical to, the analyte or analytes of interest that are added to a sample at a known concentration. An internal standard is used for quantitation of 1,4-dioxane and to account for matrix effects or variability in instrument response by normalizing the response of 1,4-dioxane, or both, thereby decreasing measurement bias to the extent that their behavior mimics that of 1,4-dioxane.
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Related to Internal standard

  • national standard means a standard adopted by a national standardisation organisation and made available to the general public;

  • international standard means a standard adopted by an international standardisation organisation and made available to the general public;

  • National Standards means the document entitled “National Standards for the Volatile Organic Compound Content of Canadian Commercial/Industrial Surface Coating Products Automotive Refinishing, October 1998, PN 1288" and published by the Canadian Council of Ministers of the Environment;

  • Technical standard means a document that specifies design, predicted performance and operation and maintenance specifications for a material, device or method.

  • Technical Standards means the technical standards set out in paragraph 2.4 of the Order Form;

  • Internal Systems means the internal systems of each of the Corporation that are presently used in its Business or operations, including, computer hardware systems, software applications and embedded systems.

  • Service Level Standards has the meaning ascribed thereto in Section 2.1 hereof.

  • Internal combustion engine or ‘engine’ means an energy converter, other than a gas turbine, designed to transform chemical energy (input) into mechanical energy (output) with an internal combustion process; it includes, where they have been installed, the emission control system and the communication interface (hardware and messages) between the engine's electronic control unit(s) and any other powertrain or non-road mobile machinery control unit necessary to comply with Chapters II and III;

  • Common Reporting Standard means the standard for automatic exchange of financial account information in tax matters (which includes the Commentaries), developed by the OECD, with G20 countries;

  • Internal control means a process effected by an entity's governing board, management, and other personnel, designed to provide reasonable assurance regarding the achievement of objectives in the following categories:

  • Internal Controls has the meaning set forth in Section 4.07(d).

  • Internal Use means use of the Sprinklr Services for Customer’s and/or Customer Affiliates’ general business use, solely for the benefit of Customer and/or Customer Affiliates, but does not include use of the Sprinklr Services to provide any services for the benefit of third parties.

  • Common Reporting Standard (CRS) means the Standard for Automatic Exchange of Financial Account Information (“AEOFAI”) in Tax Matters and was developed in response to the G20 request and approved by the Organisation for Economic Co-operation and Development (OECD) Council on 15 July 2014, calls on jurisdictions to obtain information from their financial institutions and automatically exchange that information with other jurisdictions on an annual basis. It sets out the financial account information to be exchanged, the financial institutions required to report, the different types of accounts and taxpayers covered, as well as common due diligence procedures to be followed by financial institutions.

  • Reliability Standard means a requirement to provide for reliable operation of the bulk power system, including without limiting the foregoing requirements for the operation of existing bulk power system facilities, including cybersecurity protection, and the design of planned additions or modifications to such facilities to the extent necessary for reliable operation of the bulk power system, but shall not include any requirement to enlarge bulk power system facilities or to construct new transmission capacity or generation capacity.

  • Reliability Standards means the criteria, standards, rules and requirements relating to reliability established by a Standards Authority.

  • Internal Control Event means a material weakness in, or fraud that involves management or other employees who have a significant role in, the Company’s internal controls over financial reporting, in each case as described in the Securities Laws.

  • Environmental Standards means regulations or certification specifications governing the certification of designs with regard to noise characteristics and exhaust emissions of civil aeronautical products and appliances.

  • Internal Costs means as defined in paragraph 1.1 of Schedule 4 (Heads of Expenditure) (and shall, for the avoidance of doubt, not include any revenue costs or capital investment relating to the implementation of any project pursuant to an Annual Business Plan) and excluding Joint Committee Costs

  • Internal Collaboration means collaborative arrangements within a group of companies or within various strategic business. units/subsidiaries/operating divisions in order to gain a strategic position whilst sharing resources, profits and losses as well as risks

  • auditing standards means auditing standards as defined in National Instrument 52-107 Acceptable Accounting Principles and Auditing Standards;

  • Financial Reporting Measure means any measure determined and presented in accordance with the accounting principles used in preparing the Company’s financial statements, and any measures derived wholly or in part from such measures, including GAAP, IFRS and non-GAAP/IFRS financial measures, as well as stock or share price and total equityholder return.

  • Reliability means the degree of performance of the elements of the electric system that results in electricity being delivered to and from an applicant in the amount desired while avoiding adverse effects on the adequacy and security of the electric supply, defined respectively as:

  • Professional Staff means the Medical Staff, Dental Staff, Midwifery Staff and Extended Class Nursing Staff;

  • Internal control over financial reporting means a process effected by an insurer’s board of directors, management and other personnel designed to provide reasonable assurance regarding the reliability of the financial statements, i.e., those items specified in Section 5(B)(2) through 5(B)(7) of this regulation and includes those policies and procedures that:

  • Environmental and Social Standards or “ESSs” means, collectively: (i) “Environmental and Social Standard 1: Assessment and Management of Environmental and Social Risks and Impacts”; (ii) “Environmental and Social Standard 2: Labor and Working Conditions”; (iii) “Environmental and Social Standard 3: Resource Efficiency and Pollution Prevention and Management”;

  • Internal Market Buyer means a Market Buyer making purchases of energy from the PJM Interchange Energy Market for ultimate consumption by end-users inside the PJM Region that are served by Network Transmission Service.