Target Gene definition

Target Gene means the specific gene that is the target for disruption. “Targeting Vectors” means DNA constructs used to produce ES Cells.
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Target Gene means the specific gene that is the target for disruption.
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Target Gene means each of Fabry Target Gene, Pompe Target Gene, [***] Target Gene, Additional Target Gene, subject to Section 5.1, and Option Target Gene, subject to Section 5.2 (collectively, the “Target Genes”).
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Examples of Target Gene in a sentence

  • Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control.

  • The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.

  • Collectively, these results showed that Alkbh5 expression in melanoma modulates metabolite and cytokine content with the most significant change of lactate in TIF, suggesting another mechanism by which m6A demethylase could modulate the in- filtration of immune cells during anti–PD-1/GVAX treatment.MEDICAL SCIENCESMct4/Slc16a3, an Alkbh5 Target Gene, Is Involved in Regulating Extracellular Lactate Concentration, Tregs, and MDSC Accumulation in the TME.

  • The Drug Target Gene Set Hallmark view outperforms data–specific views in Irinotecan and Panobinostat sensitivity predictions.

  • For most compounds the Drug Target Gene Set Hallmark is more accurate than the Oncogenic and Immunologic.

  • The failure of Introgen to develop successfully any Target Gene Therapy Product will not in and of itself constitute a breach by Introgen of any representation, warranty, covenant or other obligation under this Agreement, the Delivery Technology License Agreement or the Target Gene License Agreement.

  • Given 317 Manitoba’s position, the City retained separate counsel, Mr. Bowles, to represent it on the disqualification motion.

  • Without limiting the foregoing provision of this Section 2.5, nothing herein shall be deemed to grant to Gendux rights with respect to any gene other than a Target Gene, or for any product that includes any subject matter not expressly included within the Field.

  • Gendux and Introgen shall establish a research committee to oversee, review and coordinate the research and development of Target Gene Therapy Products for applications within the Field pursuant to the R&D Program (the "Research Committee").

  • Introgen shall provide to Gendux with periodic reports, as reasonably requested by Gendux (but no more frequently than one each calendar quarter), summarizing (a) the work performed hereunder by Introgen and its R&D Personnel during such quarter and (b) any material developments with respect to the Target Gene Therapy Products during such quarter.


More Definitions of Target Gene

Target Gene means (i) a gene which has been linked to a particular area of a chromosome and which is believed to be involved in or associated with the pathogenesis of brain cancer or prostate cancer and which has been selected by the research steering Committee (as defined in Section 2.3) as a target for Discovery in the Research Program and (ii) the MMAC1 brain cancer gene.
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Target Gene means a gene or sequence that is described, referenced or otherwise included in the DeltaBase Information by Deltagen.
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Target Gene means the [***] or any other gene, the Modulation of which would lead to the Treatment of [***].
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Target Gene means [ * ].
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Target Gene means the [ * ] and which is included in a Phenotype Set in accordance with Exhibit D that is Delivered to Merck by Deltagen hereunder as part of the DeltaBase Information.
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Related to Target Gene

  • KPI Target means the acceptable performance level for a KPI as set out in each KPI;

  • Target means Trans-European Automated Real-time Gross Settlement Express Transfer payment system.

  • TARGET 2 means the Trans-European Automated Real-time Gross Settlement Express Transfer payment system which utilises a single shared platform and which was launched on 19 November 2007.

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Soft Target means a target that will suffer minimum damage and cause minimum damage to the subject vehicle in the event of a collision.

  • Targets means pre-agreed values to be achieved at the end of the period in relation to the result indicators included under a specific objective;

  • Target Population means persons with low incomes who have one or more disabilities, including mental illness, HIV or AIDS, substance abuse, or other chronic health condition, or individuals eligible for services provided pursuant to the Lanterman Developmental Disabilities Services Act (Division 4.5 (commencing with Section 4500) of the Welfare and Institutions Code) and may include, among other populations, adults, emancipated minors, families with children, elderly persons, young adults aging out of the foster care system, individuals exiting from institutional settings, veterans, and homeless people.

  • Development Milestone Event has the meaning set forth in Section 7.2.1.

  • Acquisition Target means any Person becoming a Subsidiary of the Company after the date hereof; any Person that is merged into or consolidated with the Company or any Subsidiary of the Company after the date hereof; or any Person with respect to which all or a substantial part of that Person’s assets are acquired by the Company or any Subsidiary of the Company after the date hereof.

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Back-Up Compound means, with reference to any particular Development Candidate or Drug Product Candidate, a Compound which (a) has the same principal mode of action (i.e., Potentiator or Corrector) as that Development Candidate or Drug Product Candidate; and (b) was among the group of Compounds, identified by VERTEX as potential additional lead molecules having the same principal mode of action, from which the Development Candidate was selected.

  • Antibody means a molecule comprising or containing one or more immunoglobulin variable domains or any fragments, derivatives, variants or modifications thereof that bind to the same antigen.

  • Development Milestone is defined in Section 5.3.

  • Milestone Event has the meaning set forth in Section 8.2.1.

  • Antigen means a substance recognized by the body as being foreign; it results in the production of specific antibodies directed against it.

  • Milestone Events has the meaning set forth in Section 7.2.

  • Milestone 1 means achievement of annual Net Sales of at least $20,000,000 during the Calendar Year ending on December 31, 2021.

  • Development Candidate means a Compound that meets the Development Candidate Criteria for the initiation of a Development Program for the treatment of CF, and which is the subject of a notice from Vertex to CFFT that Vertex intends to commence formal pre-clinical development of the Compound in the Field pursuant to the provisions of Section 3.1 hereof.

  • Development Milestone Payment shall have the meaning set forth in Section 9.2(a).

  • Collaboration Product means a pharmaceutical product containing or comprising Compound in any dosage form alone, or in combination with, one or more other pharmaceutically active ingredients, and any and all Improvements thereto.

  • Opioid antagonist means a drug that binds to opioid

  • Product Candidate means any pharmaceutical product developed, manufactured and/or tested by or on behalf of the Company that has not received a Regulatory Authorization for commercial distribution other than in connection with pre-clinical or clinical trials.

  • DNA profile means a letter or number code which represents a set of identification characteristics of the non-coding part of an analysed human DNA sample, i.e. the particular molecular structure at the various DNA locations (loci);

  • Diagnostic Product means any test or assay for diagnosing or detecting a disease, disorder, medical condition, or symptom.

  • Milestone 2 means achievement of annual Net Sales of at least $35,000,000 during any Calendar Year ending on or before December 31, 2024.

  • Therapeutic Product means a health product categorised as a therapeutic product in the First Schedule to the Act;