Common use of Accrual of Interest; Defaulted Amounts Clause in Contracts

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 Section 2.12. Removal of Transfer Restrictions 25 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 Section 2.16. Notes Held by the Company or its Affiliates 26 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 Section 3.01. Payment on Notes 28 Section 3.02. Exchange Act Reports 28 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 Section 3.05. Compliance and Default Certificates 30 Section 3.06. Stay, Extension and Usury Laws 30 Section 3.07. Corporate Existence 31 Article 4. Repurchase and Redemption 31 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 70

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 15 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 15 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 16 Section 2.08. Holder Lists 18 17 Section 2.09. Legends 19 17 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 18 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 22 Section 2.12. Removal of Transfer Restrictions 25 23 Section 2.13. Replacement Notes 26 24 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 24 Section 2.15. Cancellation 26 24 Section 2.16. Notes Held by the Company or its Affiliates 26 24 Section 2.17. Temporary Notes 27 25 Section 2.18. Outstanding Notes 27 25 Section 2.19. Repurchases by the Company 28 26 Section 2.20. CUSIP and ISIN Numbers 28 26 Article 3. Covenants 28 26 Section 3.01. Payment on Notes 28 26 Section 3.02. Exchange Act Reports 28 26 Section 3.03. Rule 144A Information 29 27 Section 3.04. Additional Interest 29 27 Section 3.05. Compliance and Default Certificates 30 28 Section 3.06. Stay, Extension and Usury Laws 30 28 Section 3.07. Corporate Existence 31 29 Section 3.08. Restriction on Acquisition of Notes by the Company and its Affiliates 29 Section 3.09. Further Instruments and Acts 29 Article 4. Repurchase and Redemption 31 Xxxxxxxxxx 00 Section 4.01. No Sinking Fund 31 29 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7029

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 18 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 27 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 28 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 29 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 30 Section 3.04. Additional Interest 29 30 Section 3.05. Compliance and Default Certificates 30 31 Section 3.06. Stay, Extension and Usury Laws 30 31 Section 3.07. Corporate Existence 31 Acquisition of Notes by the Company and its Affiliates 32 Article 4. Repurchase and Redemption 31 32 Section 4.01. No Sinking Fund 31 32 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon Upon a Fundamental Change 31 32 Section 4.03. Right of the Company to Redeem the Notes 35 36 Article 5. Conversion 38 39 Section 5.01. Right to Convert 38 39 Section 5.02. Conversion Procedures 41 44 Section 5.03. Settlement upon Upon Conversion 43 45 Section 5.04. Reserve and Status of Common Stock Issued upon Upon Conversion 46 49 Section 5.05. Adjustments to the Conversion Rate 46 50 Section 5.06. Voluntary Adjustments 57 61 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 61 Section 5.08. Exchange in Lieu of Conversion 59 63 Section 5.09. Effect of Common Stock Change Event 59 63 Article 6. Successors 61 65 Section 6.01. When the Company May Merge, Etc. 61 65 Section 6.02. Successor Corporation Entity Substituted 62 66 Section 6.03. Exclusion for Asset Transfers with Wholly Owned Subsidiaries 66 Article 7. Defaults and Remedies 62 66 Section 7.01. Events of Default 62 66 Section 7.02. Acceleration 64 68 Section 7.03. Sole Remedy for a Failure to Report 64 69 Section 7.04. Other Remedies Cumulative 65 70 Section 7.05. Waiver of Past Defaults 66 70 Section 7.06. Control by Majority 66 70 Section 7.07. Limitation on Suits 66 71 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 71 Section 7.09. Collection Suit by Trustee 67 71 Section 7.10. Trustee May File Proofs of Claim 67 72 Section 7.11. Priorities 68 72 Section 7.12. Undertaking for Costs 68 73 Article 8. Amendments, Supplements and Waivers 68 73 Section 8.01. Without the Consent of Holders 68 73 Section 8.02. With the Consent of Holders 69 74 Section 8.03. Notice of Amendments, Supplements and Waivers 7075 Section 8.04. Revocation, Effect and Solicitation of Consents; Special Record Dates; Etc. 75 Section 8.05. Notations and Exchanges 76 Section 8.06. Trustee to Execute Supplemental Indentures 76 Article 9. Satisfaction and Discharge 76 Section 9.01. Termination of Company’s Obligations 76 Section 9.02. Repayment to Company 77 Section 9.03. Reinstatement 77 Article 10. Trustee 78 Section 10.01. Duties of the Trustee 78 Section 10.02. Rights of the Trustee 79 Section 10.03. Individual Rights of the Trustee 80 Section 10.04. Trustee’s Disclaimer 80 Section 10.05. Notice of Defaults 80 Section 10.06. Compensation and Indemnity 81 Section 10.07. Replacement of the Trustee 82 Section 10.08. Successor Trustee by Merger, Etc. 82 Section 10.09. Eligibility; Disqualification 83 Article 11. Miscellaneous 83 Section 11.01. Notices 83 Section 11.02. Delivery of Officer’s Certificate and Opinion of Counsel as to Conditions Precedent 85 Section 11.03. Statements Required in Officer’s Certificate and Opinion of Counsel 85 Section 11.04. Rules by the Trustee, the Registrar, the Paying Agent and the Conversion Agent 85 Section 11.05. No Personal Liability of Directors, Officers, Employees and Stockholders 85 Section 11.06. Governing Law; Waiver of Jury Trial 86 Section 11.07. Submission to Jurisdiction 86 Section 11.08. No Adverse Interpretation of Other Agreements 86 Section 11.09. Successors 86 Section 11.10. Force Majeure 86 Section 11.11. U.S.A. PATRIOT Act. 87 Section 11.12. Calculations 87 Section 11.13. Severability 87 Section 11.14. Counterparts 87 Section 11.15. Table of Contents, Headings, Etc. 87 Section 11.16. Withholding Taxes 88 Exhibit A: Form of Note X-0 Xxxxxxx X-0: Form of Restricted Note Legend B1-1 Exhibit B-2: Form of Global Note Legend B2-1 Exhibit B-3: Form of Affiliate Resale Legend B3-1 INDENTURE, dated as of July 6, 2022, between Cytokinetics, Incorporated, a Delaware corporation, as issuer (the “Company”), and U.S. Bank Trust Company, National Association, as trustee (the “Trustee”). Each party to this Indenture (as defined below) agrees as follows for the benefit of the other party and for the equal and ratable benefit of the Holders (as defined below) of the Company’s 3.50% Convertible Senior Notes due 2027 (the “Notes”).

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 18 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 19 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 27 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 28 Section 2.19. Repurchases by the Company 28 29 Section 2.20. CUSIP and ISIN Numbers 28 29 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 30 Section 3.04. Additional Interest 29 30 Section 3.05. Compliance and Default Certificates 30 31 Section 3.06. Stay, Extension and Usury Laws 30 31 Section 3.07. Corporate Existence 31 [reserved] 32 Section 3.08. Acquisition of Notes by the Company and its Affiliates 32 Article 4. Repurchase and Redemption 31 32 Section 4.01. No Sinking Fund 31 32 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7032

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 Section 2.09. Legends 19 18 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 19 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Redeemed Pursuant to a Repurchase Redemption Upon Fundamental Change or Optional Redemption 24 Section 2.12. Removal of Transfer Restrictions 25 Section 2.13. Replacement Notes 26 25 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 Section 2.16. Notes Held by the Company or its Affiliates 26 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases Repayments by the Company Prior to Maturity 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 Section 3.01. Payment on Notes 28 Section 3.02. Exchange Act Reports 28 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 Section 3.05. Additional Amounts 30 Section 3.06. Compliance and Default Certificates 30 33 Section 3.063.07. Stay, Extension and Usury Laws 30 33 Section 3.073.08. Corporate Existence 31 Acquisition of Notes by the Company and its Affiliates 34 Article 4. Repurchase and Redemption 31 34 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7034

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 Section 2.13. Replacement Notes 26 Section 2.142.13. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.152.14. Cancellation 26 Section 2.162.15. Notes Held by the Company or its Affiliates 26 Section 2.172.16. Temporary Notes 27 Section 2.182.17. Outstanding Notes 27 Section 2.192.18. Repurchases by the Company 28 Section 2.202.19. CUSIP and ISIN Numbers 28 Article 3. 3 Covenants 28 Section 3.01. Payment on Notes 28 Section 3.02. Exchange Act Reports 28 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 Section 3.05. Compliance and Default Certificates 30 Section 3.06. Stay, Extension and Usury Laws 30 Section 3.07. Corporate Existence Restriction on Acquisition of Notes by the Company and its Affiliates 31 Article 4. 4 Repurchase and Redemption 31 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7036

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 18 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 19 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 27 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 28 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP CXXXX and ISIN Numbers 28 29 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 30 Section 3.04. Additional Interest 29 30 Section 3.05. Compliance and Default Certificates 30 32 Section 3.06. Stay, Extension and Usury Laws 30 32 Section 3.07. Corporate Acquisition of Notes by the Company and its Affiliates 33 Section 3.08. Existence 31 33 Article 4. Repurchase and Redemption 31 33 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7033

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 Section 3.01. Payment on Notes 28 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 30 Section 3.05. Compliance and Default Certificates 30 32 Section 3.06. Stay, Extension and Usury Laws 30 32 Section 3.07. Corporate Existence 31 32 Section 3.08. Restriction on Acquisition of Notes by the Company and its Affiliates 33 Section 3.09. Further Instruments and Acts 33 Article 4. Repurchase and Redemption 31 33 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7033

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 30 Section 3.05. Additional Amounts 31 Section 3.06. Compliance and Default Certificates 30 33 Section 3.063.07. Stay, Extension and Usury Laws 30 34 Section 3.073.08. Corporate Existence 31 Acquisition of Notes by the Company and its Affiliates 34 Article 4. Repurchase and Redemption 31 34 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7034

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Exchange Agent 17 18 Section 2.07. Paying Agent and Conversion Exchange Agent to Hold Property in Trust 18 19 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Exchanged or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 30 Section 3.05. Compliance and Default Certificates 30 31 Section 3.06. Stay, Extension and Usury Laws 30 31 Section 3.07. Corporate Existence Acquisition of Notes by the Company, Holdings and their Respective Affiliates 31 Article 4. Repurchase and Redemption 31 32 Section 4.01. No Sinking Fund 31 32 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon Upon a Fundamental Change 31 32 Section 4.03. Right of the Company to Redeem the Notes 35 36 Article 5. Conversion 38 Exchange 39 Section 5.01. Right to Convert 38 Exchange 39 Section 5.02. Conversion Exchange Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7043

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 Section 2.09. Legends 19 18 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 19 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 Section 2.12. Removal of Transfer Restrictions 25 Section 2.13. Replacement Notes 26 25 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 Section 2.16. Notes Held by the Company or its Affiliates 26 Section 2.17. Temporary Notes 27 26 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 27 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 Section 3.01. Payment on Notes 28 Section 3.02. Exchange Act Reports 28 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 Section 3.05. Compliance and Default Certificates 30 Section 3.06. Stay, Extension and Usury Laws 30 Section 3.07. Corporate Existence 30 Section 3.08. Restriction on Acquisition of Notes by the Company and its Affiliates 30 Section 3.09. Further Instruments and Acts 31 Article 4. Repurchase and Redemption 31 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7031

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 18 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Trust. 19 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 27 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 28 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 29 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 30 Section 3.04. Additional Interest 29 Interest. 30 Section 3.05. Compliance and Default Certificates 30 31 Section 3.06. Stay, Extension and Usury Laws 30 31 Section 3.07. Corporate Existence 31 Section 3.08. Restriction on Acquisition of Notes by the Company and its Affiliates 32 Section 3.09. Further Instruments and Acts 32 Article 4. Repurchase and Redemption 31 32 Section 4.01. No Sinking Fund 31 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 Section 4.03. Right of the Company to Redeem the Notes 35 Article 5. Conversion 38 Section 5.01. Right to Convert 38 Section 5.02. Conversion Procedures 41 Section 5.03. Settlement upon Conversion 43 Section 5.04. Reserve and Status of Common Stock Issued upon Conversion 46 Section 5.05. Adjustments to the Conversion Rate 46 Section 5.06. Voluntary Adjustments 57 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 Section 5.08. Exchange in Lieu of Conversion 59 Section 5.09. Effect of Common Stock Change Event 59 Article 6. Successors 61 Section 6.01. When the Company May Merge, Etc. 61 Section 6.02. Successor Corporation Substituted 62 Article 7. Defaults and Remedies 62 Section 7.01. Events of Default 62 Section 7.02. Acceleration 64 Section 7.03. Sole Remedy for a Failure to Report 64 Section 7.04. Remedies Cumulative 65 Section 7.05. Waiver of Past Defaults 66 Section 7.06. Control by Majority 66 Section 7.07. Limitation on Suits 66 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 Section 7.09. Collection Suit by Trustee 67 Section 7.10. Trustee May File Proofs of Claim 67 Section 7.11. Priorities 68 Section 7.12. Undertaking for Costs 68 Article 8. Amendments, Supplements and Waivers 68 Section 8.01. Without the Consent of Holders 68 Section 8.02. With the Consent of Holders 69 Section 8.03. Notice of Amendments, Supplements and Waivers 7032

Accrual of Interest; Defaulted Amounts. When Payment Date is Not a Business Day 16 17 Section 2.06. Registrar, Paying Agent and Conversion Agent 17 18 Section 2.07. Paying Agent and Conversion Agent to Hold Property in Trust 18 Section 2.08. Holder Lists 18 19 Section 2.09. Legends 19 Section 2.10. Transfers and Exchanges; Certain Transfer Restrictions 20 Section 2.11. Exchange and Cancellation of Notes to Be Converted Converted, Redeemed or to Be Repurchased Pursuant to a Repurchase Upon Fundamental Change or Redemption 24 25 Section 2.12. Removal of Transfer Restrictions 25 26 Section 2.13. Replacement Notes 26 Section 2.14. Registered Holders; Certain Rights with Respect to Global Notes 26 Section 2.15. Cancellation 26 27 Section 2.16. Notes Held by the Company or its Affiliates 26 27 Section 2.17. Temporary Notes 27 Section 2.18. Outstanding Notes 27 Section 2.19. Repurchases by the Company 28 Section 2.20. CUSIP and ISIN Numbers 28 Article 3. Covenants 28 29 Section 3.01. Payment on Notes 28 29 Section 3.02. Exchange Act Reports 28 29 Section 3.03. Rule 144A Information 29 Section 3.04. Additional Interest 29 30 Section 3.05. Additional Amounts 31 Section 3.06. Compliance and Default Certificates 30 33 Section 3.063.07. Stay, Extension and Usury Laws 30 33 Section 3.073.08. Corporate Notes Acquired by the Company 34 Section 3.09. Existence 31 34 Article 4. Repurchase and Redemption 31 34 Section 4.01. No Sinking Fund 31 34 Section 4.02. Right of Holders to Require the Company to Repurchase Notes upon a Fundamental Change 31 34 Section 4.03. Right of the Company to Redeem the Notes 35 38 Article 5. Conversion 38 43 Section 5.01. Right to Convert 38 43 Section 5.02. Conversion Procedures 41 46 Section 5.03. Settlement upon Conversion 43 48 Section 5.04. Reserve and Status of Common Stock Ordinary Shares Issued upon Conversion 46 50 Section 5.05. Adjustments to the Conversion Rate 46 51 Section 5.06. Voluntary Adjustments 57 61 Section 5.07. Adjustments to the Conversion Rate in Connection with a Make-Whole Fundamental Change 57 61 Section 5.08. Exchange in Lieu of Conversion 59 63 Section 5.09. Effect of Common Stock Ordinary Share Change Event 59 64 Article 6. Successors 61 65 Section 6.01. When the Company May Merge, Etc. 61 65 Section 6.02. Successor Corporation Entity Substituted 62 66 Article 7. Defaults and Remedies 62 66 Section 7.01. Events of Default 62 66 Section 7.02. Acceleration 64 68 Section 7.03. Sole Remedy for a Failure to Report 64 69 Section 7.04. Other Remedies Cumulative 65 70 Section 7.05. Waiver of Past Defaults 66 70 Section 7.06. Control by Majority 66 70 Section 7.07. Limitation on Suits 66 71 Section 7.08. Absolute Right of Holders to Institute Suit for the Enforcement of the Right to Receive Payment and Conversion Consideration 67 71 Section 7.09. Collection Suit by Trustee 67 71 Section 7.10. Trustee May File Proofs of Claim 67 72 Section 7.11. Priorities 68 72 Section 7.12. Undertaking for Costs 68 73 Article 8. Amendments, Supplements and Waivers 68 73 Section 8.01. Without the Consent of Holders 68 73 Section 8.02. With the Consent of Holders 69 74 Section 8.03. Notice of Amendments, Supplements and Waivers 7075 Section 8.04. Revocation, Effect and Solicitation of Consents; Special Record Dates; Etc. 75 Section 8.05. Notations and Exchanges 76 Section 8.06. Trustee to Execute Supplemental Indentures 76 Article 9. Satisfaction and Discharge 76 Section 9.01. Termination of Company’s Obligations 76 Section 9.02. Repayment to Company 77 Section 9.03. Reinstatement 77 Article 10. Trustee 77 Section 10.01. Duties of the Trustee 77 Section 10.02. Rights of the Trustee 79 Section 10.03. Individual Rights of the Trustee 80 Section 10.04. Trustee’s Disclaimer 80 Section 10.05. Notice of Defaults 80 Section 10.06. Compensation and Indemnity 81 Section 10.07. Replacement of the Trustee 82 Section 10.08. Successor Trustee by Xxxxxx, Etc. 82 Section 10.09. Eligibility; Disqualification 83 Article 11. Miscellaneous 83 Section 11.01. Notices. 83 Section 11.02. Delivery of Officer’s Certificate and Opinion of Counsel as to Conditions Precedent 85 Section 11.03. Statements Required in Officer’s Certificate and Opinion of Counsel 85 Section 11.04. Rules by the Trustee, the Registrar and the Paying Agent 86 Section 11.05. No Personal Liability of Directors, Officers, Employees and Shareholders 86 Section 11.06. Governing Law; Waiver of Jury Trial 86 Section 11.07. Submission to Jurisdiction 86 Section 11.08. No Adverse Interpretation of Other Agreements 87 Section 11.09. Successors 87 Section 11.10. Force Majeure 87 Section 11.11. U.S.A. PATRIOT Act. 87 Section 11.12. Calculations 87 Section 11.13. Severability 88 Section 11.14. Counterparts 88 Section 11.15. Table of Contents, Headings, Etc. 88 Section 11.16. [Reserved] 88 Section 11.17. Foreign Account Tax Compliance Act (FATCA) 88 Exhibit A: Form of Note X-0 Xxxxxxx X-0: Form of Restricted Note Legend B1-1 Exhibit B-2: Form of Global Note Legend B2-1 Exhibit B-3: Form of Non-Affiliate Legend B3-1 INDENTURE, dated as of January 23, 2023, between SMART Global Holdings, Inc., a Cayman Islands exempted company, as issuer (the “Company”), and U.S. Bank Trust Company, National Association, as trustee (the “Trustee”). Each party to this Indenture (as defined below) agrees as follows for the benefit of the other party and for the equal and ratable benefit of the Holders (as defined below) of the Notes (as defined below).