Common use of Coded Information Clause in Contracts

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and tools. At this time, we do not know the specific details of these research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS-CoV-2) o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples samples, images and/or audio/video recordings are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer The Sponsor may use your Coded Information, biological samples, images, images and/or audio/video visual recordings, if collected as part of this study, to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and tools. At this time, we do not know the specific details of these research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image images and/or audio/video recordings recordings, if collected as part of the study, used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical institutional review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IntegReview IRB • Government or regulatory authorities • Accrediting agencies The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS-CoV- 2?) o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolsin other projects that will take place in the future. At this time, we do not know the specific details of these future research projects; however. If your biological samples are collected, your Coded Information, biological those samples, imagesand their data, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may only be used for future other research purposesif you agree under the Additional Consent Request at the end of this document.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: •  Pfizer and its representatives (including its affiliated companies) •  People and/or organizations providing services to or collaborating with Pfizer •  Any organization that obtains all or part of Pfizer's business or the rights to the product under study •  Other researchers •  Advarra IRB •  Government or regulatory authorities The above parties may use your coded information for the following purposes: •  Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management certain types of cancerous tumors o Assessing the safety of the study drug •  Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪  It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers •  Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. •  Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management AD o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples or images of you are taken during the study, those samples and images will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer may use your Your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, and images may be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS- CoV-2) o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: •  Pfizer and its representatives (including its affiliated companies) •  People and/or organizations providing services to or collaborating with Pfizer •  Any organization that obtains all or part of Pfizer's business or the rights to the product under study •  Other researchers •  Advarra IRB •  Government or regulatory authorities The above parties may use your coded information for the following purposes: •  Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS- CoV-2) o Assessing the safety of the study drug •  Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪  It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers •  Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. •  Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolsin other projects that will take place in the future. At this time, we do not know the specific details of these future research projects; however. If your biological samples are collected, your Coded Information, biological those samples, imagesand their data, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may only be used for future other research purposesif you agree under the Additional Consent Request at the end of this document.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management certain cancerous solid tumors o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management heart failure o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and tools. At this time, we do not know the specific details of these research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: •  Pfizer and its representatives (including its affiliated companies) •  People and/or organizations providing services to or collaborating with Pfizer •  Any organization that obtains all or part of Pfizer's business or the rights to the product under study •  Other researchers •  Advarra IRB •  Government or regulatory authorities The above parties may use your coded information for the following purposes: •  Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS- CoV-2) o Assessing the safety of the study drug •  Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪  It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers •  Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers o You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. •  Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: •  Pfizer and its representatives (including its affiliated companies) •  People and/or organizations providing services to or collaborating with Pfizer •  Any organization that obtains all or part of Pfizer's business or the rights to the product under study •  Other researchers •  Advarra IRB •  Government or regulatory authorities The above parties may use your coded information for the following purposes: •  Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management COVID-19 (or SARS- CoV-2) o Assessing the safety of the study drug •  Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪  It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers •  Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers researchers\ o You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. •  Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolsin other projects that will take place in the future. At this time, we do not know the specific details of these future research projects; however. If your biological samples are collected, your Coded Information, biological those samples, imagesand their data, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may only be used for future other research purposesif you agree under the Additional Consent Request at the end of this document.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug vaccine o Understanding the study and the study results and learning more about weight management modRNA vaccines o Assessing the safety of the study drug vaccine • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug vaccine ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But , but some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and tools. At this time, we do not know the specific details of these future research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical institutional review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes. Your biological samples will be used only for scientific research. Each sample will be labeled with a code so that laboratory workers testing the samples will not know who you are. Some of the samples may be stored for future testing and may be kept for up to 15 years after the study ends, at which time they will be destroyed. In addition to testing for this study, any samples left over after the study is complete may be used for additional research related to the development of products. No testing of your genetic material will be performed. You may request that your samples, if they can be identified, be destroyed at any time. Any data already collected from those samples will still be used for the study. The samples will remain the property of Pfizer and may be shared with other researchers as long as confidentiality is maintained and no testing of your genetic material will be performed. You will not be told of additional tests, nor will you receive results of any of these tests.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities • Accrediting agencies The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management lung cancer o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolsin other projects that will take place in the future. At this time, we do not know the specific details of these future research projects; however. If your biological samples are collected, your Coded Information, biological those samples, imagesand their data, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may only be used for future other research purposesif you agree under the Additional Consent Request at the end of this document.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management AD o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.

Coded Information. The link between the code and your personal information will be kept confidential by the study staff. Your Coded Information will be used by the following: • Pfizer and its representatives (including its affiliated companies) • People and/or organizations providing services to or collaborating with Pfizer • Any organization that obtains all or part of Pfizer's business or the rights to the product under study • Other researchers • Advarra IRB • Government or regulatory authorities The above parties may use your coded information for the following purposes: • Conducting the study, including: o Examining your response to the study drug o Understanding the study and the study results and learning more about weight management migraines o Assessing the safety of the study drug • Complying with legal and regulatory duties such as: o Ensuring the study is conducted according to good clinical practice o Making required disclosures to IRB(s), or government or regulatory authorities o Seeking approval from government or regulatory authorities to market the study drug ▪ It is possible that these government or regulatory authorities may disclose your Coded Information to other researchers for the conduct of future scientific research o Sharing study data with other researchers not affiliated with the study staff or Pfizer. This includes through publication on the internet or other ways. However, information that could directly identify you will not be made available to other researchers • Publishing summaries of the study results: o In medical journals o On the internet o At educational meetings of other researchers You will not be directly identified in any publication or report of the study. But some journal representatives may need access to your Coded Information to verify the study results and ensure the research meets the journal's quality standards. Also, journals may require that genetic and other information from the study that does not directly identify you be made available to other researchers for further research projects. • Improving the quality, design, and safety of this study and other research studies If biological samples are taken during the study, those samples will be handled in the same way as your Coded Information. All samples will be treated as required by law. Yes. Pfizer Your Coded Information and biological samples may use your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of this study, be used in other research projects to support and advance other scientific research projects, including improving the quality, design, and safety of other research studies, research supporting public health aims, and developing medicines, vaccines, diagnostic products, and toolshealth. At this time, we do not know the specific details of these other research projects; however, your Coded Information, biological samples, images, and/or audio/video recordings, if collected as part of the study, could be used in combination with data from other sources, not related to you or this study. Reasonable safeguards will be used to protect your Coded Information, biological samples, image and/or audio/video recordings used in any future research and may include: • Limiting access to individuals bound by duties of confidentiality • Taking steps to minimize the risk that you could be re-identified • Obtaining approval of ethical review boards Furthermore, if your Coded Information, biological samples, images and/or audio/video recordings, if collected as part of the study, have identifiers removed such that they can no longer be readily identified with you, they may be used for future research purposes.