Common use of Common Stock Held by the Company, etc Clause in Contracts

Common Stock Held by the Company, etc. Whenever the consent or approval of Holders of a specified percentage of securities is required hereunder, securities held by the Company or its Affiliates (other than subsequent Holders thereof if such subsequent Holders are deemed to be Affiliates solely by reason of their holdings of such securities) will not be counted in determining whether such consent or approval was given by the Holders of such required percentage. Very truly yours, Xtant Medical Holdings, Inc. By: /s/ Dxxxxx Xxxxxxxxxx Name: Dxxxxx Xxxxxxxxxx Title: Chief Executive Officer OrbiMed Royalty Opportunities II, LP By OrbiMed ROF II LLC, its General Partner By OrbiMed Advisors LLC, its Managing Member By: /s/ W. Xxxxxx Nxxxx Print Name: W. Xxxxxx Nxxxx Title: Member ROS Acquisition Offshore LP By OrbiMed Advisors LLC, solely in its capacity as Investment Manager By: /s/ W. Xxxxxx Nxxxx Print Name: W. Xxxxxx Nxxxx Title: Member

Common Stock Held by the Company, etc. Whenever the consent or approval of Holders of a specified percentage of securities is required hereunder, securities held by the Company or its Affiliates (other than subsequent Holders thereof if such subsequent Holders are deemed to be Affiliates solely by reason of their holdings of such securities) will not be counted in determining whether such consent or approval was given by the Holders of such required percentage. Very truly yours, Xtant Medical Holdings, Inc. By: /s/ Dxxxxx Xxxxxx Xxxxxxxxxx Name: Dxxxxx Xxxxxx Xxxxxxxxxx Title: Chief Executive Officer OrbiMed Royalty Opportunities II, LP By OrbiMed ROF II LLC, its General Partner By OrbiMed Advisors LLC, its Managing Member By: /s/ W. Xxxxxx Nxxxx Print X. Xxxxx Name: W. Xxxxxx Nxxxx X. Xxxxx Title: Member Managing member ROS Acquisition Offshore LP By OrbiMed Advisors LLC, solely in its capacity as Investment Manager By: /s/ W. Xxxxxx Nxxxx Print X. Xxxxx Name: W. Xxxxxx Nxxxx X. Xxxxx Title: MemberManaging member

Common Stock Held by the Company, etc. Whenever the consent or approval of Holders of a specified percentage of securities is required hereunder, securities held by the Company or its Affiliates (other than subsequent Holders thereof if such subsequent Holders are deemed to be Affiliates solely by reason of their holdings of such securities) will not be counted in determining whether such consent or approval was given by the Holders of such required percentage. Very truly yours, COMPANY: Xtant Medical Holdings, Inc. By: /s/ Dxxxxx Xxxxxxxxxx Sxxx Xxxxxx Name: Dxxxxx Xxxxxxxxxx Sxxx Xxxxxx Title: Chief Executive Officer OrbiMed Royalty Opportunities President, CEO EXCHANGE PARTIES: ORBIMED ROYALTY OPPORTUNITIES II, LP By OrbiMed ROF II LLC, its General Partner By OrbiMed Advisors LLC, its Managing Member By: /s/ W. Xxxxxx Nxxxx Print Name: W. Xxxxxx Nxxxx Title: Member ROS Acquisition Offshore ACQUISITION OFFSHORE LP By OrbiMed Advisors LLC, solely in its capacity as Investment Manager By: /s/ W. Xxxxxx Nxxxx Print Name: W. Xxxxxx Nxxxx Title: MemberMember ANNEX A