Melatonin Treatment Sample Clauses

Melatonin Treatment. Generally being classified as a lipophilic hormone, melatonin (N-acetyl-5- methoxytryptamine), is in fact, an important secretory product of pineal gland and a major component of the circadian system. (Xxxxxx, 2003; Xxxxxxx, et al., 2011). Suppressed by light and controlled by the suprachiasmatic nucleus (SCN), the concentration of melatonin remains at a low level during daytime and starts to rise at night during which it peaks around 2-4am. (Xxxxxxxxxx, 1997). Melatonin acts as a highly effective oxidant, and has been recently found to be a free radical scavenger. (Xxx, et al., 2003; Xxx, et al., 2009). Several studies have shown that melatonin improves antioxidative enzyme activity and reduces oxidative damage. (Xxxxxxxxx, et al., 2004; Xxxxxxxxxx, et al., 2008; Xx Xxxxxxx, et al., 2008). It is thought that melatonin also plays roles in inhibiting oxidative stress, lowering blood pressure, and potentially reducing inflammatory processes. (Xxxxxxxx-Xxxxxxxxxxx, et al., 2009; Xxxxx & Xxxxxxxxx, 2009; Xxxx, et al., 2010). Xxxxxx in 2003 reviewed several clinical aspects of melatonin with respect to its effects on the immune system, as well as its antioxidant effects. He evaluated the physiological and pharmacological benefits of melatonin administration in humans and animals and demonstrated non-toxicity of the molecule. (Xxxxxx, 2003). Studies have reported that the dosage level and time of administration is critical for the efficacy of exogenous melatonin administration. (Xxxxxxx, 1993). In addition, Xxxxx, xxx Xxxxxxx and xx Xxxxx conducted a systematic review on melatonin dose variation in 2014, and suggested that a lower supplementation level may be associated with better outcome. (Vural, van Munster, & de Rooij, 2014).
Sample 1
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Related to Melatonin Treatment

  • Medical Treatment Undersigned understands that the Released Parties do not have medical personnel available at the location of the activities. Undersigned hereby grants the Released Parties permission to administer first aid or to authorize emergency medical treatment, if necessary. Undersigned understands and agrees that any such action by the Released Parties shall be subject to the terms of this agreement and release, including any liability arising from the negligence of the Released Parties when administering first aid or authorizing others to do so. Undersigned understands and agrees that the Released Parties do not assume responsibility for any injury or damage which might arise out of or in connection with such authorized emergency medical treatment.

  • Xxx Treatment We have not promised you any particular tax outcome from buying or holding the Note.

  • Emergency Medical Treatment I grant the Releasees permission to authorize emergency medical treatment as they deem appropriate, and agree that such action by the Releasees shall be subject to the terms of this Agreement. I understand and agree that the Releasees assume no responsibility for any injury or damage that might result from such emergency medical treatment.

  • Sale Treatment The Company has determined that the disposition of the Mortgage Loans pursuant to this Agreement will be afforded sale treatment for accounting and tax purposes;

  • National Treatment In the sectors inscribed in its Schedule, and subject to any conditions and qualifications set out therein, each Party shall accord to services and service suppliers of the other Party treatment no less favourable than that it accords, in like circumstances, to its own services and service suppliers.

  • National Treatment and Most-favoured-nation Treatment (1) Each Contracting Party shall accord to investments of investors of the other Contracting Party, treatment which shall not be less favourable than that accorded either to investments of its own or investments of investors of any third State. (2) In addition, each Contracting Party shall accord to investors of the other Contracting Party, including in respect of returns on their investments, treatment which shall not be less favourable than that accorded to investors of any third State. (3) The provisions of paragraphs (1) and (2) above shall not be construed so as to oblige one Contracting Party to extend to the investors of the other the benefit of any treatment, preference or privilege resulting from: (a) Any existing or future free trade area, customs unions, monetary union or similar international agreement or other forms of regional cooperation to which one of the Contracting Parties is or may become a party, or (b) Any matter pertaining wholly or mainly to taxation.

  • REIT Treatment The Company will use its reasonable efforts to enable the Company to continue to meet the requirements to qualify for taxation as a REIT under the Code for subsequent tax years that include any portion of the term of this Agreement except as otherwise determined by the Board of Directors of the Company to be in the best interests of stockholders.

  • Consistent Treatment Unless and until there has been a Final Determination to the contrary, each Party agrees not to take any position on any Tax Return, in connection with any Tax Contest or otherwise that is inconsistent with (i) the treatment of payments between the Parent Group and the SpinCo Group as set forth in Section 5.4, (ii) the Tax Materials or (iii) the Intended Tax Treatment.

  • Denial of Preferential Tariff Treatment The Customs Authority of the importing Party may deny a claim for preferential tariff treatment when: (a) the good does not qualify as an originating good; or (b) the importer, exporter or producer fails to comply with any of the relevant requirements of this Chapter.

  • Equal Treatment No consideration shall be offered or paid to any person to amend or consent to a waiver or modification of any provision of the Transaction Documents unless the same consideration is also offered and paid to all the Subscribers and their permitted successors and assigns.

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