Common use of Proof of Concept Development Plan Clause in Contracts

Proof of Concept Development Plan. As promptly as practicable after AVEO has prepared the Proof of Concept Development Plan, AVEO shall provide a copy thereof to Biogen Idec for its review and comment. Biogen Idec shall have a period of [**] to review and comment on the Proof of Concept Development Plan. AVEO shall consider in good faith all reasonable comments made by Biogen Idec to the Proof of Concept Development Plan. If and to the extent requested by Biogen Idec, appropriate members of the clinical development and regulatory teams of AVEO shall meet with appropriate members of the clinical development and regulatory teams of Biogen Idec to discuss the Proof of Concept Study, including the design thereof as well as the Licensed Product and indication being studied in the Proof of Concept Study, and the Development activities and timelines contemplated under the Proof of Concept Development Plan. AVEO may amend, modify, supplement or update the Proof of Concept Development Plan at any time and from time to time in its discretion, provided that AVEO complies with the foregoing provisions of this Section 2.5 (but with Biogen Idec having a [**] review period instead of [**]) with respect to any such amendment, modification, supplement or update of the Proof of Concept Development Plan to the same extent as AVEO is required in connection with the initial Proof of Concept Development Plan, and any such amendment, modification, supplement or update of the Proof of Concept Development Plan is consistent with the parameters set forth in the next sentence. The Proof of Concept Development Plan proposed by AVEO hereunder, including any amendment, modification, supplement or update, shall meet the following parameters: [**].