Common use of Record Tracking Clause in Contracts

Record Tracking. Status: Original 11-Jun-20 | 10:16 Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx Location: DocuSign Signer Events Signature Timestamp Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 Sent: 11-Jun-20 | 10:24 Viewed: 12-Jun-20 | 14:52 Signed: 12-Jun-20 | 14:53 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 122.15.2.242 Sent: 12-Jun-20 | 14:53 Viewed: 15-Jun-20 | 07:39 Signed: 19-Jun-20 | 09:08 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 210.212.103.9 Sent: 19-Jun-20 | 09:08 Viewed: 24-Jun-20 | 10:52 Signed: 24-Jun-20 | 11:03 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 24-Jun-20 | 11:03 Resent: 24-Jun-20 | 18:02 Viewed: 24-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp Witness Events Signature Timestamp Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 | 18:54 Certified Delivered Security Checked 25-Jun-20 | 02:57 Signing Complete Security Checked 25-Jun-20 | 03:01 Completed Security Checked 25-Jun-20 | 03:01

Record Tracking. Status: Original 11-Jun-20 | 10:16 3/9/2021 10:35:21 AM Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx EcoDev xxxxxx@xxxxxxxxxxx.xxx Location: DocuSign Signer Events Signature Timestamp Xxxxx Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx xxx@xxxxxxxxxxxx.xxx Co-owner Security Level: Email, Account Authentication (None) Signature Adoption: Drawn on Device Using IP Address: 138.128.130.156 Sent: 3/9/2021 10:36:44 AM Viewed: 3/11/2021 7:16:49 PM Signed: 3/11/2021 7:19:36 PM Electronic Record and Signature Disclosure: Accepted: 3/11/2021 7:16:49 PM ID: d917a52d-07fa-473f-93c7-c2588924b405 Cam Xxxxxx xxxxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 72.16.81.2 Sent: 11-Jun-20 | 10:24 3/11/2021 7:19:38 PM Viewed: 12-Jun-20 | 14:52 3/12/2021 8:25:59 AM Signed: 12-Jun-20 | 14:53 3/12/2021 8:26:07 AM Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx Accepted: 3/12/2021 8:25:59 AM ID: 3bb0d7d6-72a1-44cb-8d50-2a7ce8c383de Xxxxxx Xxxxxx III xxxxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 122.15.2.242 72.16.81.2 Sent: 12-Jun-20 | 14:53 3/12/2021 8:26:08 AM Viewed: 15-Jun-20 | 07:39 3/12/2021 12:38:56 PM Signed: 19-Jun-20 | 09:08 3/12/2021 12:39:25 PM Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Security LevelAccepted: Email, Account Authentication (None) Signature Adoption3/12/2021 12:38:56 PM ID: Preb4e24cf2-selected Style Using IP Address: 210.212.103.9 Sent: 194452-Jun-20 | 09:08 Viewed: 2441a9-Jun-20 | 10:52 Signed: 24bf30-Jun-20 | 11:03 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 24-Jun-20 | 11:03 Resent: 24-Jun-20 | 18:02 Viewed: 24-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign 5f1b3fe60d99 In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp Xxxx Xxxxxx xxxxxxx@xxxxxxxxxxx.xxx Records Information Manager City of Sugar Land Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Eco Dev E-Mail Address xxxxxx@xxxxxxxxxxx.xxx Department Account City of Sugar Land Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Xxxx Xxxx xxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Sent: 3/12/2021 12:39:26 PM Sent: 3/12/2021 12:39:27 PM Sent: 3/12/2021 12:39:27 PM Witness Events Signature Timestamp Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 | 18:54 3/9/2021 10:36:44 AM Certified Delivered Security Checked 25-Jun-20 | 02:57 3/12/2021 12:38:56 PM Signing Complete Security Checked 25-Jun-20 | 03:01 3/12/2021 12:39:25 PM Completed Security Checked 253/12/2021 12:39:27 PM Payment Events Status Timestamps Electronic Record and Signature Disclosure Electronic Record and Signature Disclosure created on: 3/20/2017 2:02:24 PM Parties agreed to: Xxxxx Xxxxxxx, Cam Xxxxxx, Xxxxxx Xxxxxx III ELECTRONIC RECORD AND SIGNATURE DISCLOSURE From time to time, City of Sugar Land (we, us or Company) may be required by law to provide to you certain written notices or disclosures. Described below are the terms and conditions for providing to you such notices and disclosures electronically through your DocuSign, Inc. (DocuSign) Express user account. Please read the information below carefully and thoroughly, and if you can access this information electronically to your satisfaction and agree to these terms and conditions, please confirm your agreement by clicking the 'I agree' button at the bottom of this document. Getting paper copies At any time, you may request from us a paper copy of any record provided or made available electronically to you by us. For such copies, as long as you are an authorized user of the DocuSign system you will have the ability to download and print any documents we send to you through your DocuSign user account for a limited period of time (usually 30 days) after such documents are first sent to you. After such time, if you wish for us to send you paper copies of any such documents from our office to you, you will be charged a $0.00 per-Jun-20 | 03:01page fee. You may request delivery of such paper copies from us by following the procedure described below. Withdrawing your consent If you decide to receive notices and disclosures from us electronically, you may at any time change your mind and tell us that thereafter you want to receive required notices and disclosures only in paper format. How you must inform us of your decision to receive future notices and disclosure in paper format and withdraw your consent to receive notices and disclosures electronically is described below. Consequences of changing your mind If you elect to receive required notices and disclosures only in paper format, it will slow the speed at which we can complete certain steps in transactions with you and delivering services to you because we will need first to send the required notices or disclosures to you in paper format, and then wait until we receive back from you your acknowledgment of your receipt of such paper notices or disclosures. To indicate to us that you are changing your mind, you must withdraw your consent using the DocuSign 'Withdraw Consent' form on the signing page of your DocuSign account. This will indicate to us that you have withdrawn your consent to receive required notices and disclosures electronically from us and you will no longer be able to use your DocuSign Express user account to receive required notices and consents electronically from us or to sign electronically documents from us. All notices and disclosures will be sent to you electronically Unless you tell us otherwise in accordance with the procedures described herein, we will provide electronically to you through your DocuSign user account all required notices, disclosures, authorizations, acknowledgements, and other documents that are required to be provided or made available to you during the course of our relationship with you. To reduce the chance of you inadvertently not receiving any notice or disclosure, we prefer to provide all of the required notices and disclosures to you by the same method and to the same address that you have given us. Thus, you can receive all the disclosures and notices electronically or in paper format through the paper mail delivery system. If you do not agree with this process, please let us know as described below. Please also see the paragraph immediately above that describes the consequences of your electing not to receive delivery of the notices and disclosures electronically from us. How to contact City of Sugar Land: You may contact us to let us know of your changes as to how we may contact you electronically, to request paper copies of certain information from us, and to withdraw your prior consent to receive notices and disclosures electronically as follows: To contact us by email send messages to: xxxxxxx@xxxxxxxxxxx.xxx To advise City of Sugar Land of your new e-mail address To let us know of a change in your e-mail address where we should send notices and disclosures electronically to you, you must send an email message to us at xxxxxxx@xxxxxxxxxxx.xxx and in the body of such request you must state: your previous e-mail address, your new e-mail address. We do not require any other information from you to change your email address.. In addition, you must notify DocuSign, Inc to arrange for your new email address to be reflected in your DocuSign account by following the process for changing e-mail in DocuSign. To request paper copies from City of Sugar Land To request delivery from us of paper copies of the notices and disclosures previously provided by us to you electronically, you must send us an e-mail to xxxxxxx@xxxxxxxxxxx.xxx and in the body of such request you must state your e-mail address, full name, US Postal address, and telephone number. We will xxxx you for any fees at that time, if any. To withdraw your consent with City of Sugar Land To inform us that you no longer want to receive future notices and disclosures in electronic format you may:

Record Tracking. Status: Original 11-Jun-20 | 10:16 Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx Xxxxxxxx Xxxxxxxxx Location: DocuSign 6/20/2014 11:51:06 AM ET xxxxxxxxxx@xxxxxxxxx.xxx Signer Events Signature Timestamp Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx XxXxxxx Docusigned by: Sent: 6/24/2014 4:30:22 PM ET /s/ Xxxxx XxXxxxx Viewed: 6/24/2014 4:31:44 PM ET xxxx.xxxxxxxxx@xxxxxxx.xxx A54C2D48588B48F... Signed: 6/25/2014 2:49:32 PM ET Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 Sent: 11-Jun-20 | 10:24 Viewed: 12-Jun-20 | 14:52 Signed: 12-Jun-20 | 14:53 Electronic Record and Signature Disclosure: Using IP Address: 204.14.70.178 Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx ID: Xxxx Xxxxxxxxx Docusigned by Sent: 6/25/2014 2:49:33 PM ET /s/ Xxxx Xxxxxxxxx Viewed: 6/25/2014 3:02:54 PM ET XxxxxxxxxX@XxxXxxxxx.xxx 96962A7213E74AD... Signed: 6/25/2014 3:03:49 PM ET SVP Development Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 122.15.2.242 Sent: 12-Jun-20 | 14:53 Viewed: 15-Jun-20 | 07:39 Signed: 19-Jun-20 | 09:08 199.68.16.14 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Security LevelID: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 210.212.103.9 Sent: 19-Jun-20 | 09:08 Viewed: 24-Jun-20 | 10:52 Signed: 24-Jun-20 | 11:03 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 24-Jun-20 | 11:03 Resent: 24-Jun-20 | 18:02 Viewed: 24-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp Witness Xxxxxxx XxXxxxxx COPIED Sent: 6/25/2014 3:03:49 PM ET xxxxxxx.xxxxxxxx@xxxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxx Xxxxxxxxx COPIED Sent: 6/25/2014 3:03:50 PM ET xxxx.xxxxxxxxx@xxxxxxx.xxx Security Level: Email, Account Authentication (None) Carbon Copy Events Status Timestamp Electronic Record and Signature Timestamp Disclosure: Not Offered ID: Xxxx Xxxxx COPIED Sent: 6/25/2014 3:03:51 PM ET XxxxxXXxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxxxxxx Xxxxxxxxx III COPIED Sent: 6/25/2014 3:03:52 PM ET xxxxxxxxxx@xxxxxxxxx.xxx MedImmune Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxxxxxxx, Xxxxx COPIED Sent: 6/25/2014 3:03:52 PM ET XxxxxxxxxX@XxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxx Xxxxxxx COPIED Sent: 6/25/2014 3:03:53 PM ET XxxxxxxX@XxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 | 18:54 6/25/2014 3:03:53 PM ET Certified Delivered Security Checked 25-Jun-20 | 02:57 6/25/2014 3:03:53 PM ET Signing Complete Security Checked 25-Jun-20 | 03:01 6/25/2014 3:03:53 PM ET Completed Security Checked 6/25/2014 3:03:53 PM ET xxx.xxxxxxxxxxxxxxxxxxxxxx.xxx June 30, 2014 MedImmune, LLC Xxx XxxXxxxxx Xxx Xxxxxxxxxxxx, XX 00000 Attention: EVP, Research Facsimile: (000) 000-0000 MedImmune, LLC Xxx XxxXxxxxx Xxx Xxxxxxxxxxxx, XX 00000 Attention: Legal Department Facsimile: (000) 000-0000 Re: License and Option Agreement Ladies and Gentlemen: Reference is made to the License and Option Agreement, effective as of July 24, 2013, by and between MedImmune, LLC and Bulldog Pharmaceuticals, Inc., as amended by that certain letter agreement dated February 10, 2014 and the Addendum to the License and Option Agreement, executed as of June 25-Jun-20 | 03:01, 2014 (collectively, the “Agreement”). Capitalized terms used but not defined in this letter have the meanings given to them in the Agreement. The Parties desire (x) to clarify and supplement certain of their rights and obligations under the Agreement with respect to the Inventory and (y) to clarify their intention regarding the definition of MedImmune Manufacturing Information and Inventions. Accordingly, the Parties agree as follows:

Record Tracking. Status: Original 11-Jun-20 | 10:16 Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx Jxxxx Hxxxxxx Technology Ventures Location: DocuSign December 12, 2023 | 09:48 jxxx-xxxxxxxxxx@xx.xxx Signer Events Signature Timestamp Bxxxxxx Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx /s/ Bxxxxxx Xxxxxxx Sent: December 12, 2023 | 09:48 bxxxxx00@xx.xxx Viewed: December 12, 2023 | 09:56 Sr. Administrator Coordinator Signed: December 12, 2023 | 09:57 JHTV Security Level: Email, Account Authentication (None) Signature Adoption: Drawn on Device Using IP Address: 162.129.251.21 Electronic Record and Signature Disclosure: Not Offered via DocuSign Vxxx Xxxxxxx /s/ Vxxx Xxxxxxx Sent: December 12, 2023 | 09:57 vxxxxxx0@xx.xxx Viewed: December 12, 2023 | 11:17 Security Level: Email, Account Authentication Signed: December 12, 2023 | 11:17 (None) Signature Adoption: Pre-selected Style Using IP Address: 162.129.250.60 Electronic Record and Signature Disclosure: Accepted: December 12, 2023 | 11:17 ID: 02a7e742-9571-4c1b-bc4d-f4581ed66f5c Jxxxxxx Xxxxxxxxxx /s/ Jxxxxxx Xxxxxxxxxx Sent: December 12, 2023 | 11:17 jxxxxxx0@xx.xxx Viewed: December 12, 2023 | 11:19 Director of Licensing Signed: December 12, 2023 | 11:19 Security Level: Email, Account Authentication (None) Signature Adoption: Drawn on Device Using IP Address: 162.129.252.234 Electronic Record and Signature Disclosure: Accepted: September 12, 2022 | 18:29 ID: 3dc2a7d3-ffcd-45d8-b1a9-e7d1f8bfc2b4 Fxxxxxx X. X’Xxxxxxx, Xx., MD /s/ Fxxxxxx X. X’Xxxxxxx, Xx., MD Sent: December 12, 2023 | 11:19 fxxxxxx@xxxxx.xxx Viewed: December 12, 2023 | 11:43 Security Level: Email, Account Authentication Signed: December 12, 2023 | 11:43 (None) Signature Adoption: Pre-selected Style Using IP Address: 75.146.136.118 Electronic Record and Signature Disclosure: Accepted: December 12, 2023 | 11:43 ID: 44bf3cac-7e95-42f6-b5f4-73615749928d Sxxxxx X. Xxxxxxxxx /s/ Sxxxxx X. Xxxxxxxxx Sent: December 12, 2023 | 11:43 sxxxxxx0@xxx.xxx Viewed: December 12, 2023 | 11:44 Executive Director - JHTV Signed: December 12, 2023 | 11:44 The Jxxxx Hxxxxxx University Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 Sent: 11-Jun-20 | 10:24 Viewed: 12-Jun-20 | 14:52 Signed: 12-Jun-20 | 14:53 162.129.252.228 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx Security LevelAccepted: EmailDecember 12, Account Authentication (None) Signature Adoption2023 | 11:44 ID: Pre990a9e78-selected Style Using IP Address: 122.15.2.242 Sent: 129e3c-4b2a-Jun-20 | 14:53 Viewed: 15-Jun-20 | 07:39 Signed: 19-Jun-20 | 09:08 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 210.212.103.9 Sent: 19-Jun-20 | 09:08 Viewed: 24-Jun-20 | 10:52 Signed: 24-Jun-20 | 11:03 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 24-Jun-20 | 11:03 Resent: 24-Jun-20 | 18:02 Viewed: 24-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign be2f-0094e743deae In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp Witness Events Signature Timestamp Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 December 12, 2023 | 18:54 09:48 Certified Delivered Security Checked 25-Jun-20 December 12, 2023 | 02:57 11:44 Signing Complete Security Checked 25-Jun-20 December 12, 2023 | 03:01 11:44 Completed Security Checked 25December 12, 2023 | 11:44 Payment Events Status Timestamps Electronic Record and Signature Disclosure Electronic Record and Signature Disclosure created on: January 31, 2018 | 09:24 Parties agreed to: Vxxx Xxxxxxx, Jxxxxxx Xxxxxxxxxx, Fxxxxxx X. X’Xxxxxxx, Xx., MD, Sxxxxx X. Xxxxxxxxx ELECTRONIC RECORD AND SIGNATURE DISCLOSURE From time to time, The Jxxxx Hxxxxxx University, through its Jxxxx Hxxxxxx Technology Ventures (“JHTV”) office, may be required by law to provide to you certain written notices or disclosures. Described below are the terms and conditions for providing to you such notices and disclosures electronically through your DocuSign, Inc. (“DocuSign”) Express user account. Please read the information below carefully and thoroughly, and if you can access this information electronically to your satisfaction and agree to these terms and conditions, please confirm your agreement by clicking the ‘I agree’ button at the bottom of this document. Getting paper copies At any time, you may request from us a paper copy of any record provided or made available electronically to you by us. For such copies, as long as you are an authorized user of the DocuSign system you will have the ability to download and print any documents we send to you through your DocuSign user account for a limited period of time (usually 30 days) after such documents are first sent to you. After such time, if you wish for us to send you paper copies of any such documents from our office to you, you will be charged a $[[0.00]] per-Jun-20 | 03:01page fee. You may request delivery of such paper copies from us by following the procedure described below. Withdrawing your consent If you decide to receive notices and disclosures from us electronically, you may at any time change your mind and tell us that thereafter you want to receive required notices and disclosures only in paper format. How you must inform us of your decision to receive future notices and disclosure in paper format and withdraw your consent to receive notices and disclosures electronically is described below. Consequences of changing your mind If you elect to receive required notices and disclosures only in paper format, it will slow the speed at which we can complete certain steps in transactions with you and delivering services to you because we will need first to send the required notices or disclosures to you in paper format, and then wait until we receive back from you your acknowledgment of your receipt of such paper notices or disclosures. To indicate to us that you are changing your mind, you must withdraw your consent using the DocuSign ‘Withdraw Consent’ form on the signing page of your DocuSign account. This will indicate to us that you have withdrawn your consent to receive required notices and disclosures electronically from us and you will no longer be able to use your DocuSign Express user account to receive required notices and consents electronically from us or to sign electronically documents from us. All notices and disclosures will be sent to you electronically Unless you tell us otherwise in accordance with the procedures described herein, we will provide electronically to you through your DocuSign user account all required notices, disclosures, authorizations, acknowledgements, and other documents that are required to be provided or made available to you during the course of our relationship with you. To reduce the chance of you inadvertently not receiving any notice or disclosure, we prefer to provide all of the required notices and disclosures to you by the same method and to the same address that you have given us. Thus, you can receive all the disclosures and notices electronically or in paper format through the paper mail delivery system. If you do not agree with this process, please let us know as described below. Please also see the paragraph immediately above that describes the consequences of your electing not to receive delivery of the notices and disclosures electronically from us. To advise JHTV of your new e-mail address To let us know of a change in your e-mail address where we should send notices and disclosures electronically to you, you must send an email message to us at the appropriate email address from those listed in the “How to contact JHTV” Section above and in the body of such request you must state: your previous e-mail address and your new e-mail address. In addition, you must notify DocuSign, Inc to arrange for your new email address to be reflected in your DocuSign account by following the process for changing e-mail in DocuSign. To request paper copies from JHTV To request delivery from us of paper copies of the notices and disclosures previously provided by us to you electronically, you must send us an e-mail, using one of the designated email accounts above, and in the body of such request you must state your e-mail address, full name, US Postal address, and telephone number. To withdraw your consent with JHTV To inform us that you no longer want to receive future notices and disclosures in electronic format you may:

Record Tracking. Status: Original 11-Jun-20 | 10:16 Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx Xxxxxxxx Xxxxxxxxx Location: DocuSign 6/20/2014 11:51:06 AM ET xxxxxxxxxx@xxxxxxxxx.xxx Signer Events Signature Timestamp Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx XxXxxxx Docusigned by: Sent: 6/24/2014 4:30:22 PM ET /s/ Xxxxx XxXxxxx Viewed: 6/24/2014 4:31:44 PM ET xxxx.xxxxxxxxx@xxxxxxx.xxx A54C2D48588B48F... Signed: 6/25/2014 2:49:32 PM ET Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 Sent: 11-Jun-20 | 10:24 Viewed: 12-Jun-20 | 14:52 Signed: 12-Jun-20 | 14:53 Electronic Record and Signature Disclosure: Using IP Address: 204.14.70.178 Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx ID: Xxxx Xxxxxxxxx Docusigned by Sent: 6/25/2014 2:49:33 PM ET /s/ Xxxx Xxxxxxxxx Viewed: 6/25/2014 3:02:54 PM ET XxxxxxxxxX@XxxXxxxxx.xxx 96962A7213E74AD... Signed: 6/25/2014 3:03:49 PM ET SVP Development Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 122.15.2.242 Sent: 12-Jun-20 | 14:53 Viewed: 15-Jun-20 | 07:39 Signed: 19-Jun-20 | 09:08 199.68.16.14 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Security LevelID: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 210.212.103.9 Sent: 19-Jun-20 | 09:08 Viewed: 24-Jun-20 | 10:52 Signed: 24-Jun-20 | 11:03 Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 24-Jun-20 | 11:03 Resent: 24-Jun-20 | 18:02 Viewed: 24-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp Witness Xxxxxxx XxXxxxxx COPIED Sent: 6/25/2014 3:03:49 PM ET xxxxxxx.xxxxxxxx@xxxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxx Xxxxxxxxx COPIED Sent: 6/25/2014 3:03:50 PM ET xxxx.xxxxxxxxx@xxxxxxx.xxx Security Level: Email, Account Authentication (None) Carbon Copy Events Status Timestamp Electronic Record and Signature Timestamp Disclosure: Not Offered ID: Xxxx Xxxxx COPIED Sent: 6/25/2014 3:03:51 PM ET XxxxxXXxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxxxxxx Xxxxxxxxx III COPIED Sent: 6/25/2014 3:03:52 PM ET xxxxxxxxxx@xxxxxxxxx.xxx MedImmune Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxxxxxxx, Xxxxx COPIED Sent: 6/25/2014 3:03:52 PM ET XxxxxxxxxX@XxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Xxxx Xxxxxxx COPIED Sent: 6/25/2014 3:03:53 PM ET XxxxxxxX@XxxXxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered ID: Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 | 18:54 6/25/2014 3:03:53 PM ET Certified Delivered Security Checked 25-Jun-20 | 02:57 6/25/2014 3:03:53 PM ET Signing Complete Security Checked 25-Jun-20 | 03:01 6/25/2014 3:03:53 PM ET Completed Security Checked 6/25/2014 3:03:53 PM ET xxx.xxxxxxxxxxxxxxxxxxxxxx.xxx June 30, 2014 MedImmune, LLC Onx XxxXxxxxx Xxx Xxxxxxxxxxxx, XX 00000 Attention: EVP, Research Facsimile: (000) 000-0000 MedImmune, LLC Onx XxxXxxxxx Xxx Xxxxxxxxxxxx, XX 00000 Attention: Legal Department Facsimile: (000) 000-0000 Re: License and Option Agreement Ladies and Gentlemen: Reference is made to the License and Option Agreement, effective as of July 24, 2013, by and between MedImmune, LLC and Bulldog Pharmaceuticals, Inc., as amended by that certain letter agreement dated February 10, 2014 and the Addendum to the License and Option Agreement, executed as of June 25-Jun-20 | 03:01, 2014 (collectively, the “Agreement”). Capitalized terms used but not defined in this letter have the meanings given to them in the Agreement. The Parties desire (x) to clarify and supplement certain of their rights and obligations under the Agreement with respect to the Inventory and (y) to clarify their intention regarding the definition of MedImmune Manufacturing Information and Inventions. Accordingly, the Parties agree as follows:

Record Tracking. Status: Original 11-Jun-20 | 10:16 3/3/2021 5:06:13 PM Holder: Conference Proceedings xxxxxxxxxxxxxxxxxxxxx@xxxxxxxx.xxx EcoDev xxxxxx@xxxxxxxxxxx.xxx Location: DocuSign Signer Events Signature Timestamp Xxxxxxx Xxxxx x.xxxxx@xxxxxxxx.xxx Xxxxxx xxxxxxxxxxx@xxxxx.xxx owner Bagel Mania/Bagel Mania Too Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 94.194.197.251 206.54.196.238 Sent: 11-Jun-20 | 10:24 3/3/2021 5:07:27 PM Viewed: 12-Jun-20 | 14:52 3/3/2021 6:06:24 PM Signed: 12-Jun-20 | 14:53 3/3/2021 6:06:33 PM Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx.X.X. Xxxxxxx xxxxxxxxx@xxxxxxxxx.xxx Accepted: 6/16/2020 7:27:32 AM ID: 88bbeb9f-f0f4-4e40-9c69-8731ccc2c217 Cam Xxxxxx xxxxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 122.15.2.242 72.16.81.2 Sent: 12-Jun-20 | 14:53 3/3/2021 6:06:35 PM Viewed: 15-Jun-20 | 07:39 3/4/2021 8:52:45 AM Signed: 19-Jun-20 | 09:08 3/4/2021 8:52:55 AM Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxxx Prasad xxxxxxx@xxxxx.xxx.xx Accepted: 3/4/2021 8:52:45 AM ID: 6264bcb0-3445-4000-a314-041447a07488 Xxxxxx Xxxxxx III xxxxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Using IP Address: 210.212.103.9 72.16.81.2 Sent: 19-Jun-20 | 09:08 3/4/2021 8:52:56 AM Viewed: 24-Jun-20 | 10:52 3/4/2021 9:33:04 AM Signed: 24-Jun-20 | 11:03 3/4/2021 9:33:17 AM Electronic Record and Signature Disclosure: Not Offered via DocuSign Xx. Xxxxxx Xxxxxx xxxxxxxxxxxx.xxx@xxxxx.xx.xx Security LevelAccepted: Email, Account Authentication (None) Signature Adoption3/4/2021 9:33:04 AM ID: Pre078d7d40-selected Style Using IP Address: 106.207.188.123 Signed using mobile Sent: 246172-Jun-20 | 11:03 Resent: 244178-Jun-20 | 18:02 Viewed: 2495d3-Jun-20 | 18:48 Signed: 24-Jun-20 | 18:54 Electronic Record and Signature Disclosure: Not Offered via DocuSign Signer Events Signature Timestamp Xx. Xxxxxx Xxxxx Sent: 24-Jun-20 | 18:54 xxxxxxxxxxx.xxx@xxxxx.xx.xx Viewed: 25-Jun-20 | 02:57 Security Level: Email, Account Authentication (None) Signature Adoption: Pre-selected Style Signed: 25-Jun-20 | 03:01 Using IP Address: 157.47.250.44 Signed using mobile Electronic Record and Signature Disclosure: Not Offered via DocuSign 651f083a146e In Person Signer Events Signature Timestamp Editor Delivery Events Status Timestamp Agent Delivery Events Status Timestamp Intermediary Delivery Events Status Timestamp Certified Delivery Events Status Timestamp Carbon Copy Events Status Timestamp City Sec E-Mail Address xxxxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Eco Dev E-Mail Address xxxxxx@xxxxxxxxxxx.xxx Department Account City of Sugar Land Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Xxxx Xxxx xxxxx@xxxxxxxxxxx.xxx Security Level: Email, Account Authentication (None) Electronic Record and Signature Disclosure: Not Offered via DocuSign Sent: 3/4/2021 9:33:18 AM Viewed: 3/4/2021 9:34:42 AM Sent: 3/4/2021 9:33:18 AM Resent: 3/4/2021 9:33:20 AM Sent: 3/4/2021 9:33:19 AM Witness Events Signature Timestamp Notary Events Signature Timestamp Envelope Summary Events Status Timestamps Envelope Sent Hashed/Encrypted 24-Jun-20 | 18:54 3/3/2021 5:07:27 PM Certified Delivered Security Checked 25-Jun-20 | 02:57 3/4/2021 9:33:04 AM Signing Complete Security Checked 25-Jun-20 | 03:01 3/4/2021 9:33:17 AM Completed Security Checked 253/4/2021 9:33:19 AM Payment Events Status Timestamps Electronic Record and Signature Disclosure Electronic Record and Signature Disclosure created on: 3/20/2017 2:02:24 PM Parties agreed to: Xxxxx Xxxxxx, Cam Xxxxxx, Xxxxxx Xxxxxx XXX ELECTRONIC RECORD AND SIGNATURE DISCLOSURE From time to time, City of Sugar Land (we, us or Company) may be required by law to provide to you certain written notices or disclosures. 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Please also see the paragraph immediately above that describes the consequences of your electing not to receive delivery of the notices and disclosures electronically from us. How to contact City of Sugar Land: You may contact us to let us know of your changes as to how we may contact you electronically, to request paper copies of certain information from us, and to withdraw your prior consent to receive notices and disclosures electronically as follows: To contact us by email send messages to: xxxxxxx@xxxxxxxxxxx.xxx To advise City of Sugar Land of your new e-mail address To let us know of a change in your e-mail address where we should send notices and disclosures electronically to you, you must send an email message to us at xxxxxxx@xxxxxxxxxxx.xxx and in the body of such request you must state: your previous e-mail address, your new e-mail address. We do not require any other information from you to change your email address.. 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