Reduced dose of GP IIb Sample Clauses

Reduced dose of GP IIb. IIIa receptor antagonists Although GPIIb/IIIa inhibitors are routinely used in clinical practice, increased concern of bleeding complications and their potential effect on outcomes, has led to re-evaluation of our strategies and set the pace for studies investigating the safety and efficacy of bolus-only GPIIb/IIIa receptor antagonists schemes241. In a study reporting single-center experience with 1001 patients, bolus-only dosing schemes of abciximab, tirofiban and eptifibatide resulted in low rates of in-hospital death (0.1%), myocardial infarction (4.3%), and repeat revasculariza- tion (0%) that are comparable to the outcomes observed when mainstream dosing schemes are followed, while achieving lower rates of major or minor bleeding (2.3%)242. However, since this was an observational and not a randomized trial, the results must be cautiously evalu- ated.
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