Xxxxxx Lines Sample Clauses

Xxxxxx Lines. P. mirabilis has been observed to form boundaries called “Dienes lines” resulting from intersecting swarm fronts of different strains (283). Dienes lines do not form between swarm fronts of the same strain which suggests P. mirabilis possesses a mechanism to distinguish self from non-self. This mechanism was recently found to be mediated by the ids (identification of self) and idr loci (284, 285). Ids and Idr function independently of each other but share the same type-VI secretion system (tss) (285). Type-VI secretion systems in Gram-negative bacteria can deliver toxins into neighboring bacteria causing cell death (286). Conflicting results exist as to whether the boundaries formed by different P. mirabilis strains result from killing (287) or strain-to-strain avoidance mediated by a diffusible signal (284, 288). The ids and idr discrimination loci are only expressed in swarming bacteria as if they anticipate combat with other bacteria as they move through their environment. The study of these systems will shed light on multicellular interactions and niche dominance.
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