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Xxxxxx Xxxx X. Xxxxxxxx, Xxxxxx X. Xxxxxxxxx, Xxx Xxx, and Xxxxxxx X. X. Xxxx* Abstract: The creation of adaptive matter is heavily inspired by biological systems. However, it remains challenging to design complex material responses that are governed by reaction networks, which lie at the heart of cellular complexity. The main reason for this slow progress is the lack ofa general strategy to integrate reaction networks with materials. Herein we use a systematic approach to preprogram the response of a hydrogel to a trigger, in this case the enzyme trypsin, which activates a reaction network embedded within the hydrogel. A full characterization of all the kinetic rate constants in the system enabled the construction of a computational model, which predicted different hydrogel responses depending on the input concentration of the trigger. The results of the simulation are in good agreement with experimental findings. Our methodology can be used to design new, adaptive materials of which the properties are governed by reaction networks of arbitrary complexity.
Xxxxxx Xxxx X. Xxxxxx and Xxxxxxxxx Xxxxxxxx join in this Lease for the sole purpose of subordinating their respective dower and curtesy interest in the Property to the terms and conditions of this Agreement of Lease.
Xxxxxx Xxxx XXxxxxx Xxxxx Xxxxxxx If one or more of these arbitrators becomes permanently unable to serve on the panel, the parties shall mutually agree to a replacement(s). Until the parties so agree, the remaining arbitrators shall constitute the panel. When panel membership changes, a new addendum shall be added to the Agreement indicating the change.
Xxxxxx Xxxx X. Xxxx@xxxx.xxx Xxxxx Xxxxxxxxx X.Xxxxxxxxx@xxxx.xxx Xxxxxxxx Xxxxxxxxx Xxxxxxxx.Xxxxxxxxx@xxxxxxxxxx.xxx Xxxxxx Xxxxxxxxxx Wetzlerova Xxxxxxxxxx@xxxx.xx Xxx Xxxxxxxxxxxxx Xxxxxxxxxxxxx@xxxx.xx Xxxxxxx Xxxxxxxx Xxxxxxx.Xxxxxxxx@xxxxxxxxxx.xxx
Xxxxxx Xxxx X. Xxx Xxxx X. Xxxxxxxx Xxxxx Xxxxxxx Xxxxxx X. Xxxxxx A. Xxxxx Xxxxxxxx
Xxxxxx Xxxx X. Xxxxxx, Xxxx Xxxxx, Xxxxx Xxxxxx, Xxxx Xxxxxxx and Xxxxx Xxxxx or knowledge of such persons of facts or circumstances that would lead a prudent person to investigate and, more likely than not, acquire actual knowledge.
Xxxxxx Xxxx X. Xxxxxx Exhibit A-1 FORM OF OPINION OF COMPANY'S GENERAL COUNSEL TO BE DELIVERED PURSUANT TO SECTION 5(b)
Xxxxxx Xxxx X. Xxxxx and J. Xxxxx Xxxxx, stockholders of TPC, have agreed to tender all of their TPC Common Stock pursuant to the Offer.
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