Penwest Pharmaceuticals Co Sample Contracts

LEASE AGREEMENT
Lease Agreement • May 15th, 2003 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Connecticut
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Exhibit 10.1 PENWEST PHARMACEUTICALS CO. SECURITIES PURCHASE AGREEMENT AUGUST 4, 2003
Securities Purchase Agreement • August 6th, 2003 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York
RECITALS
Services Agreement • June 22nd, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
PURCHASE AGREEMENT
Purchase Agreement • November 5th, 2002 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York
SUPPLY AGREEMENT
Supply Agreement • June 22nd, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • London
AND RIGHTS AGENT
Rights Agreement • July 17th, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
AGREEMENT
Confidentiality Agreement • October 21st, 1997 • Penwest Pharmaceuticals Co • Stockholm
AND
Strategic Alliance Agreement • August 14th, 2002 • Penwest Pharmaceuticals Co • Pharmaceutical preparations
RECITALS
Employee Benefits Agreement • June 22nd, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
RECITALS
Separation and Distribution Agreement • June 22nd, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
RIGHTS AGREEMENT between Penwest Pharmaceuticals Co. and Mellon Investor Services LLC, as Rights Agent Dated March 11, 2009
Rights Agreement • March 12th, 2009 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York

RIGHTS AGREEMENT, dated March 11, 2009 (the “Agreement”), between Penwest Pharmaceuticals Co., a Washington corporation (the “Company”), and Mellon Investor Services LLC, a New Jersey limited liability company, as Rights Agent (the “Rights Agent”).

RECITALS
Services Agreement • November 10th, 1997 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
MANUFACTURE AND SUPPLY AGREEMENT BETWEEN
Manufacture and Supply Agreement • March 16th, 2007 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Quebec
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AS LENDER) AND
Financing Agreement • May 15th, 2001 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York
RECITALS
Separation Agreement • November 10th, 1997 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
1. DEFINITIONS
Custom Manufacturing Agreement • March 21st, 2000 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York
RECITALS:
Excipient Supply Agreement • June 22nd, 1998 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Washington
CONFIDENTIALITY AGREEMENT
Confidentiality Agreement • August 20th, 2010 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Pennsylvania

THIS AGREEMENT is entered into as of the 30th of July 2010 and shall be deemed to be effective as of July 23, 2010 between Endo Pharmaceuticals Inc., whose main offices are located at 100 Endo Boulevard, Chadds Ford, Pennsylvania 19317, for itself and its subsidiaries, each of which shall be bound by this Agreement as if each had separately executed this Agreement (collectively “Endo”), and Penwest Pharmaceuticals Co. located at 2981 Route 22, Patterson, NY 12563 ( “Penwest”).

LETTER OF CONSENT
Letter of Consent • October 21st, 1997 • Penwest Pharmaceuticals Co • Stockholm
AGREEMENT AND PLAN OF MERGER BY AND AMONG ENDO PHARMACEUTICALS HOLDINGS INC. WEST ACQUISITION CORP. AND PENWEST PHARMACEUTICALS CO. DATED AS OF AUGUST 9, 2010
Merger Agreement • August 10th, 2010 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • Delaware

THIS AGREEMENT AND PLAN OF MERGER (this “Agreement”), dated as of August 9, 2010, is by and among Endo Pharmaceuticals Holdings Inc., a Delaware corporation (“Parent”), West Acquisition Corp., a Delaware corporation and an indirect, wholly-owned Subsidiary of Parent (“Merger Sub”), and Penwest Pharmaceuticals Co., a Washington corporation (the “Company”).

SECOND AMENDMENT TO THE AMENDED AND RESTATED STRATEGIC ALLIANCE AGREEMENT BY AND BETWEEN PENWEST PHARMACEUTICALS CO AND ENDO PHARMACEUTICALS INC
Strategic Alliance Agreement • November 10th, 2008 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York

This Second Amendment (this “Amendment”) to the Amended and Restated Strategic Alliance Agreement dated as of April 2, 2002, and as amended by the Amendment Agreement dated January 7, 2007 (the “Agreement”) is entered into by and between Penwest Pharmaceuticals Co (“Penwest”) and Endo Pharmaceuticals Inc. (“Endo”), effective as of July 14, 2008.

SIXTH AMENDMENT
Strategic Alliance Agreement • August 10th, 2010 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York

This Sixth Amendment (the “Sixth Amendment”), dated as of August 9, 2010, but effective as set forth in Paragraph 10 below, to the Amended and Restated Strategic Alliance Agreement (as amended) is entered into by and between PENWEST PHARMACEUTICALS CO., a corporation organized and existing under the laws of the State of Washington, with its principal place of business at 39 Old Ridgebury Road, Danbury, Connecticut 06810 (“Penwest”), and ENDO PHARMACEUTICALS INC., a corporation organized and existing under the laws of the State of Delaware, with its principal place of business at 100 Painters Drive, Chadds Ford, Pennsylvania 19317 (“Endo”) (each, a “Party” and collectively, the “Parties”).

AMENDMENT NO. 3 TO RIGHTS AGREEMENT
Rights Agreement • April 23rd, 2008 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York

This AMENDMENT NO. 3 TO RIGHTS AGREEMENT (the “Amendment”) is entered into as of April 18, 2008, between Penwest Pharmaceuticals Co., a Washington corporation (the “Company”), and Mellon Investor Services LLC, a New Jersey limited liability company, as Rights Agent (the “Rights Agent”). Capitalized terms not otherwise defined herein shall have the meanings given them in the Rights Agreement dated as of July 27, 1998, as amended by Amendment No. 1 and Amendment No. 2 thereto (the “Rights Agreement”), between the parties hereto.

THIRD AMENDMENT TO THE AMENDED AND RESTATED STRATEGIC ALLIANCE AGREEMENT BY AND BETWEEN PENWEST PHARMACEUTICALS CO. AND ENDO PHARMACEUTICALS INC.
Strategic Alliance Agreement • May 11th, 2009 • Penwest Pharmaceuticals Co • Pharmaceutical preparations • New York

This Third Amendment (this “Amendment”) to the Amended and Restated Strategic Alliance Agreement dated as of April 2, 2002, and as amended by the Amendment Agreement dated January 7, 2007 and further amended by the Second Amendment dated as of July 14, 2008 (the “Agreement”) is entered into by and between Penwest Pharmaceuticals Co. (“Penwest”) and Endo Pharmaceuticals Inc. (“Endo”), effective as of January 1, 2009.

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