THIS EMPLOYMENT AGREEMENT dated for reference the 6th day of August, 2008 BETWEEN:Employment Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
THEREFORE in consideration of the recitals, the following covenants and the payment of one dollar made by each party to the other, the receipt and sufficiency of which is acknowledged by each party, the parties agree on the following terms:
Helix BioPharma Corp. STOCK OPTION AGREEMENT (2008 Option Plan - Director)Stock Option Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations
TECHNOLOGY LICENSE AGREEMENT CONFIDENTIAL TREATMENT REQUESTEDTechnology License Agreement • March 2nd, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
INFORMATION FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED IS OMITTED AND IS IDENTIFIED BY THREE ASTERISKS, AS FOLLOWS “* * *”, AN UNREDACTED VERSION OF THIS DOCUMENT HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.
CLINICAL SUPPLIES MANUFACTURING AGREEMENT BETWEEN HELIX BIOPHARMA CORP. AND BIOVECTRA INC. May 4, 2008 CONFIDENTIAL TREATMENT REQUESTEDCGMP Process Development, Scale Up and Clinical Supplies Manufacturing Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
INFORMATION FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED IS OMITTED AND IS IDENTIFIED BY THREE ASTERISKS, AS FOLLOWS “* * *”, AN UNREDACTED VERSION OF THIS DOCUMENT HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.
Material Transfer and License Option Agreement between Helix BioPharma Corporation and Schering CorporationMaterial Transfer and License Option Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • New York
INFORMATION FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED IS OMITTED AND IS IDENTIFIED BY THREE ASTERISKS, AS FOLLOWS “* * *”, AN UNREDACTED VERSION OF THIS DOCUMENT HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.
SECOND AMENDED AND RESTATED FINANCIAL AND INVESTOR RELATIONS AGREEMENT This Agreement is dated effective as of January 28, 2011.Financial and Investor Relations Agreement • November 1st, 2011 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
WHEREAS Helix previously retained ACM to provide Helix with investor and financial advisory services in Europe, by execution of the Financial and Investor Relations Agreement dated as of January 25, 2010 (hereinafter referred to as the “Original Agreement”);
Helix BioPharma Corp. STOCK OPTION AGREEMENT (2000 Option Plan - Directors Only)Stock Option Agreement • November 25th, 2008 • Helix BioPharma Corp
TOPICAL INTERFERON ALPHA-2b GMP PROCESS DEVELOPMENT, SCALE UP AND CLINICAL SUPPLIES MANUFACTURING AGREEMENT BETWEEN HELIX BIOPHARMA CORP. AND CONTRACT PHARMACEUTICALS LIMITED NIAGARA April _3__, 2008 CONFIDENTIAL TREATMENT REQUESTEDTopical Interferon Alpha-2b GMP Process Development, Scale Up and Clinical Supplies Manufacturing Agreement • February 4th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
INFORMATION FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED IS OMITTED AND IS IDENTIFIED BY THREE ASTERISKS, AS FOLLOWS “* * *”, AN UNREDACTED VERSION OF THIS DOCUMENT HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.
THIS AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of October, 2009 (the “Amendment”). BETWEEN:Employment Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations
THIS AGREEMENT made as of the ___ day of January, 2006.Indemnification & Liability • February 4th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
SUBSCRIPTION AGREEMENT FOR UNITS HELIX BIOPHARMA CORP. THE UNITS BEING OFFERED FOR SALE MAY ONLY BE PURCHASED BY ELIGIBLE PURCHASERS RESIDENT IN THE UNITED STATES IMPORTANTSubscription Agreement • April 5th, 2011 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
SUBSCRIPTION AGREEMENTSubscription Agreement • August 17th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
This Agreement will outline the general terms and conditions under which the Subscriber proposes to purchase Units of Helix BioPharma Corp.
THIS SECOND AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of August, 2010 (the “Amendment”).Employment Agreement • October 29th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations
THIS SECOND AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of August, 2010 (the “Amendment”).Employment Agreement • October 29th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations
FINDERS AGREEMENT This Agreement is dated effective as of July 1, 2009.Finders Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
HELIX BIOPHARMA CORP. having an office at 3-305 Industrial Parkway South, Aurora, Ontario, Canada (hereinafter referred to as "Helix")
THIS AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of October, 2009 (the “Amendment”). BETWEEN:Employment Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations
SECOND AMENDMENT TO MANUFACTURING AGREEMENTManufacturing Agreement • September 20th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations
This second amendment agreement (“Second Amendment”) is made this 18 day of November, 2009 by and between Helix Biopharma Corporation (“Helix”), a corporation organized and existing under the laws of Canada and having its principal offices located at 305 Industrial Parkway South, Unit 3, Aurora, Ontario, L4G 6X7, and Contract Pharmaceuticals Limited Niagara (“CPL”), a corporation organized and existing under the laws of Delaware and having a place of business located at 100 Forest Avenue, Buffalo, New York, 14213.
HELIX BIOPHARMA CORP. HAS REQUESTED AN ORDER FROM THE SECURITIES AND EXCHANGE COMMISSION (THE “COMMISSION”) PURSUANT TO RULE 24B-2 OF THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED, GRANTING CONFIDENTIAL TREATMENT OF SELECTED PORTIONS OF THIS...Manufacturing Agreement • November 1st, 2011 • Helix BioPharma Corp • Pharmaceutical preparations
This third amendment agreement (“Third Amendment”) is made this 1 day of October, 2010 by and between Helix Biopharma Corporation (“Helix”), a corporation organized and existing under the laws of Canada and having its principal offices located at 305 Industrial Parkway South, Unit 3, Aurora, Ontario, L4G 6X7, Contract Pharmaceuticals Limited Niagara (“CPL”), a corporation organized and existing under the laws of Delaware and having a place of business located at 100 Forest Avenue, Buffalo, New York, 14213, and Contract Pharmaceuticals Limited Canada (“CPL Canada”), a corporation organized and existing under the laws of Ontario, Canada and having its principal offices at 7600 Danbro Crescent, Mississauga, Ontario, Canada, L5N 6L6.
INDEMNITY AGREEMENT THIS AGREEMENT made as of ______, 20__.Indemnification Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
NOW THEREFORE, in consideration of the premises, the mutual covenants and agreements contained herein and other good and valuable consideration, the receipt and adequacy whereof are hereby acknowledged, the parties do hereby agree as follows:
THIS AGREEMENT made as of the ___ day of January, 2006.Indemnification Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
Helix BioPharma Corp. STOCK OPTION AGREEMENT (2010 Equity Compensation Plan – Directors and Officers)Stock Option Agreement • November 1st, 2011 • Helix BioPharma Corp • Pharmaceutical preparations
TOPICAL INTERFERON ALPHA-2b GMP PROCESS DEVELOPMENT, SCALE UP AND CLINICAL SUPPLIES MANUFACTURING AGREEMENT BETWEEN HELIX BIOPHARMA CORP. AND CONTRACT PHARMACEUTICALS LIMITED NIAGARA April _3__, 2008 CONFIDENTIAL TREATMENT REQUESTEDGMP Process Development and Manufacturing Agreement • February 5th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
INFORMATION FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED IS OMITTED AND IS IDENTIFIED BY THREE ASTERISKS, AS FOLLOWS “* * *”, AN UNREDACTED VERSION OF THIS DOCUMENT HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.
TECHNOLOGY LICENCE AGREEMENT AMENDMENTTechnology License Agreement • November 1st, 2011 • Helix BioPharma Corp • Pharmaceutical preparations
AMENDED AND RESTATED FINANCIAL AND INVESTOR RELATIONS AGREEMENT This Agreement is dated effective as of June 28, 2010.Financial and Investor Relations Agreement • August 17th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations • Ontario
WHEREAS Helix previously retained ACM to provide Helix with investor and financial advisory services in Europe, by execution of the Financial and Investor Relations Agreement dated as of January 25, 2010 (hereinafter referred to as the “Original Agreement”); and
THIS SECOND AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of August, 2010 (the “Amendment”).Employment Agreement • October 29th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations
THIS AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of October, 2009 (the “Amendment”). BETWEEN:Employment Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations
THIS AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of October, 2009 (the “Amendment”). BETWEEN:Employment Agreement • October 29th, 2009 • Helix BioPharma Corp • Pharmaceutical preparations
THIS SECOND AMENDMENT TO EMPLOYMENT AGREEMENT dated for reference the 1st day of August, 2010 (the “Amendment”).Employment Agreement • October 29th, 2010 • Helix BioPharma Corp • Pharmaceutical preparations
