Celgene European Investment Co LLC Sample Contracts

JOINT FILING AGREEMENT
Joint Filing Agreement • August 6th, 2013 • Celgene European Investment Co LLC • Pharmaceutical preparations

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need be filed with respect to the ownership by each of the undersigned of shares of stock of Agios Pharmaceuticals, Inc.

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AGIOS PHARMACEUTICALS, INC. SERIES B CONVERTIBLE PREFERRED STOCK PURCHASE AGREEMENT Dated as of April 14, 2010
Series B Convertible Preferred Stock Purchase Agreement • August 6th, 2013 • Celgene European Investment Co LLC • Pharmaceutical preparations • Delaware

This Agreement (“Agreement”) dated as of April 14, 2010 is entered into by and among Agios Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Celgene Corporation, a Delaware corporation (the “Purchaser”).

ADOPTION AGREEMENT
Adoption Agreement • April 30th, 2014 • Celgene European Investment Co LLC • Pharmaceutical preparations

This Adoption Agreement (the “Adoption Agreement”) is executed on April 29, 2014, by the undersigned (the “Holder”) pursuant to the terms of that certain Second Amended and Restated Investor Rights Agreement dated as of November 16, 2011 (the “Agreement”), by and among Agios Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the Purchasers listed therein, as such Agreement may be amended or amended and restated hereafter. Capitalized terms used but not defined in this Adoption Agreement shall have the respective meanings ascribed to such terms in the Agreement. By the execution of this Adoption Agreement, the Holder agrees as follows.

FORM OF LOCK-UP AGREEMENT
Lock-Up Agreement • January 23rd, 2018 • Celgene European Investment Co LLC • Pharmaceutical preparations
AGIOS PHARMACEUTICALS, INC. SERIES C-1 CONVERTIBLE PREFERRED STOCK AND SERIES C-2 CONVERTIBLE PREFERRED STOCK PURCHASE AGREEMENT Dated as of November 16, 2011
Series C-1 and C-2 Convertible Preferred Stock Purchase Agreement • August 6th, 2013 • Celgene European Investment Co LLC • Pharmaceutical preparations • Delaware

This Agreement (“Agreement”) dated as of November 16, 2011 is entered into by and among Agios Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the individuals and entities listed on Exhibit A hereto (the “Purchasers”).

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