FORM OF LOCK-UP AGREEMENTFrazier Life Sciences VIII, L.P. • July 5th, 2018 • Pharmaceutical preparations • New York
FORM OF LOCK-UP AGREEMENTMerger Agreement • July 31st, 2017 • Frazier Life Sciences VIII, L.P. • Pharmaceutical preparations • Delaware
The undersigned signatory of this lock-up agreement (this “Lock-Up Agreement”) understands that Nivalis Therapeutics, Inc., a Delaware corporation (“Nivalis”) has entered into an Agreement and Plan of Merger and Reorganization, dated as of April 18, 2017 (as the same may be amended from time to time, the “Merger Agreement”) with Nautilus Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Nivalis, and Alpine Immune Sciences, Inc., a Delaware corporation. Capitalized terms used but not otherwise defined herein shall have the respective meanings ascribed to such terms in the Merger Agreement.
AGREEMENTAgreement • July 5th, 2018 • Frazier Life Sciences VIII, L.P. • Pharmaceutical preparations
This Schedule 13D was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on July 31, 2017.
AGREEMENTAgreement • September 21st, 2021 • Frazier Life Sciences VIII, L.P. • Pharmaceutical preparations
Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need be filed with respect to the ownership by each of the undersigned of Common Stock of Alpine Immune Systems, Inc.
AGREEMENTAgreement • February 7th, 2020 • Frazier Life Sciences VIII, L.P. • Pharmaceutical preparations
This Agreement was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on July 31, 2017.
AGREEMENTAgreement • July 31st, 2017 • Frazier Life Sciences VIII, L.P. • Pharmaceutical preparations
This Schedule 13D was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney a copy of which is attached as Exhibit B.
